U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    synr sayonara [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33702, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    synrprovided by FlyBase
    Official Full Name
    sayonaraprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031650
    Locus tag
    Dmel_CG14044
    See related
    AllianceGenome:FB:FBgn0031650
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14044; Dmel\CG14044
    Summary
    Involved in positive regulation of apoptotic process. Part of Bcl-2 family protein complex. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See synr in Genome Data Viewer
    Location:
    25B4-25B4; 2-14 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4942742..4944305)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4942742..4944305)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene hoepel2 Neighboring gene Salivary gland secretion 1 Neighboring gene mitochondrial ribosomal protein L24 Neighboring gene beta subunit of type I geranylgeranyl transferase Neighboring gene jetlag Neighboring gene Jonah 25Biii

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Sayonara to some evolutionary puzzles in the Bcl-2 family. White K. EMBO J, 2023 Apr 17. PMID 36970867, Free PMC Article
    2. A feedback loop that drives cell death and proliferation and its defect in intestinal stem cells. Sulekh S, et al. Life Sci Alliance, 2024 Apr. PMID 38296349, Free PMC Article
    3. Evidence for existence of an apoptosis-inducing BH3-only protein, sayonara, in Drosophila. Ikegawa Y, et al. EMBO J, 2023 Apr 17. PMID 36727601, Free PMC Article
    4. Understanding Developmental Cell Death Using Drosophila as a Model System. Umargamwala R, et al. Cells, 2024 Feb 16. PMID 38391960, Free PMC Article
    5. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. Kanca O, et al. Elife, 2022 Jun 20. PMID 35723254, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of positive regulation of autophagy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Bcl-2 family protein complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    sayonara
    Names
    CG14044-PA
    synr-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4942742..4944305
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135035.3 → NP_608879.1  sayonara [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608879.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VMY2
      Related
      FBpp0078629
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VMY2 Q9VMY2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools