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    Tengl3 Testis EndoG-Like 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33404, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tengl3provided by FlyBase
    Official Full Name
    Testis EndoG-Like 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0051679
    Locus tag
    Dmel_CG31679
    See related
    AllianceGenome:FB:FBgn0051679
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17006; CG31679; Dmel\CG31679
    Summary
    Predicted to enable RNA endonuclease activity and single-stranded DNA endodeoxyribonuclease activity. Predicted to be involved in apoptotic DNA fragmentation. Predicted to be active in mitochondrial inner membrane and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tengl3 in Genome Data Viewer
    Location:
    22D5-22D5; 2-5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2237076..2238251, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2237076..2238251, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44114 Neighboring gene sauron Neighboring gene Secretory 24CD Neighboring gene antisense RNA:CR44115 Neighboring gene Testis EndoG-Like 2 Neighboring gene Testis EndoG-Like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Barriers to male transmission of mitochondrial DNA in sperm development. DeLuca SZ, et al. Dev Cell, 2012 Mar 13. PMID 22421049, Free PMC Article
    2. Wake-up-call, a lin-52 paralogue, and Always early, a lin-9 homologue physically interact, but have opposing functions in regulating testis-specific gene expression. Doggett K, et al. Dev Biol, 2011 Jul 15. PMID 21570388, Free PMC Article
    3. Molecular definitions of autophagy and related processes. Galluzzi L, et al. EMBO J, 2017 Jul 3. PMID 28596378, Free PMC Article
    4. A Drosophila protein-interaction map centered on cell-cycle regulators. Stanyon CA, et al. Genome Biol, 2004. PMID 15575970, Free PMC Article
    5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA endonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables single-stranded DNA endodeoxyribonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in apoptotic DNA fragmentation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    testis EndoG-Like 3
    Names
    CG31679-PA
    Tengl3-PA
    NP_608660.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2237076..2238251 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134816.3 → NP_608660.3  testis EndoG-Like 3 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608660.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQ95
      Related
      FBpp0077486
      Conserved Domains (1) summary
      smart00892
      Location:125 → 294
      Endonuclease_NS; DNA/RNA non-specific endonuclease
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQ95 Q9VQ95

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