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    CG33474 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 2768725, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG33474provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0053474
    Locus tag
    Dmel_CG33474
    See related
    AllianceGenome:FB:FBgn0053474
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG33474
    Summary
    Involved in peroxisome fission. Is active in peroxisomal membrane. Orthologous to human PEX11G (peroxisomal biogenesis factor 11 gamma). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG33474 in Genome Data Viewer
    Location:
    47A7-47A7; 2-62 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10421706..10422989)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6309211..6310494)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene slowpoke 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Peroxiredoxin 6c Neighboring gene uncharacterized protein Neighboring gene Peroxiredoxin 6b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dietary cysteine and methionine promote peroxisome elevation and fat loss by induction of CG33474 expression in Drosophila adipose tissue. Liu M, et al. Cell Mol Life Sci, 2024 Apr 22. PMID 38649521, Free PMC Article
    2. Rosy Beginnings: Studying Peroxisomes in Drosophila. Pridie C, et al. Front Cell Dev Biol, 2020. PMID 32984330, Free PMC Article
    3. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
    4. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
    5. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in peroxisome fission IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in peroxisome fission IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in peroxisome fission IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in peroxisomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in peroxisomal membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in peroxisomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG33474-PA
    CG33474-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      10421706..10422989
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206078.2 → NP_995800.1  uncharacterized protein Dmel_CG33474, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995800.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z891, D5A7K7
      Conserved Domains (1) summary
      pfam05648
      Location:1 → 194
      PEX11; Peroxisomal biogenesis factor 11 (PEX11)

    2. NM_001299358.1 → NP_001286287.1  uncharacterized protein Dmel_CG33474, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286287.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z891, D5A7K7
      Conserved Domains (1) summary
      pfam05648
      Location:1 → 194
      PEX11; Peroxisomal biogenesis factor 11 (PEX11)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z891 A1Z891

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