Gnl1 G protein nucleolar 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gnl1provided by RGD
Official Full Name: G protein nucleolar 1provided by RGD
Primary source: RGD:1303051
See related: EnsemblRapid:ENSRNOG00000000798 AllianceGenome:RGD:1303051
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable GTPase activity. Predicted to be involved in DNA damage response. Orthologous to human GNL1 (G protein nucleolar 1 (putative)). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 152.5), Kidney (RPKM 114.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 20p12

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (2787939..2796924, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (2783130..2792115, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	20	NC_005119.4 (3290543..3299494, complement)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

NoName (e-PCR)
- UniSTS:493382

RH132743 (e-PCR)
- UniSTS:216026

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA damage response	IEA Inferred from Electronic Annotation more info
involved_in DNA damage response	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info

General protein information

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Preferred Names: guanine nucleotide-binding protein-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212500.3 → NP_997665.1 guanine nucleotide-binding protein-like 1

See identical proteins and their annotated locations for NP_997665.1

Status: VALIDATED

Source sequence(s)

BC129081, BX883048

UniProtKB/Swiss-Prot

Q6MG06

UniProtKB/TrEMBL

A0A0G2K6Q5, A6KT59

Related

ENSRNOP00000098187.1, ENSRNOT00000120545.2

Conserved Domains (2) summary

cd01857
Location:177 → 418

HSR1_MMR1; A circularly permuted subfamily of the Ras GTPases

PRK09563
Location:179 → 516

rbgA; GTPase YlqF; Reviewed