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    Slc35e4 solute carrier family 35, member E4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 266687, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Slc35e4provided by RGD
    Official Full Name
    solute carrier family 35, member E4provided by RGD
    Primary source
    RGD:708484
    See related
    EnsemblRapid:ENSRNOG00000004168 AllianceGenome:RGD:708484
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable antiporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Orthologous to human SLC35E4 (solute carrier family 35 member E4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 103.6), Brain (RPKM 81.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc35e4 in Genome Data Viewer
    Location:
    14q21
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (83026914..83033778, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (78803320..78810186, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (84163971..84170835, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene transcription initiation factor IIA subunit 2-like Neighboring gene similar to human chromosome 5 open reading frame 52 Neighboring gene dual specificity phosphatase 18 Neighboring gene transcobalamin 2 Neighboring gene pescadillo ribosomal biogenesis factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC93128

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 35 member E4
    Names
    putative phosphate-phosphoenolpyruvate translocator

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153316.2 → NP_695228.2  solute carrier family 35 member E4

      See identical proteins and their annotated locations for NP_695228.2

      Status: PROVISIONAL

      Source sequence(s)
      BC085693
      UniProtKB/Swiss-Prot
      Q5RKL7
      Related
      ENSRNOP00000005646.3, ENSRNOT00000005646.6
      Conserved Domains (3) summary
      pfam00892
      Location:188 → 324
      EamA; EamA-like transporter family
      pfam03151
      Location:54 → 325
      TPT; Triose-phosphate Transporter family
      cl23754
      Location:53 → 178
      EamA; EamA-like transporter family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      83026914..83033778 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039091642.2 → XP_038947570.1  solute carrier family 35 member E4 isoform X1

      Conserved Domains (1) summary
      cl26744
      Location:54 → 182
      TPT; Triose-phosphate Transporter family

    2. XM_039091643.2 → XP_038947571.1  solute carrier family 35 member E4 isoform X2

      Conserved Domains (1) summary
      cl26744
      Location:72 → 188
      TPT; Triose-phosphate Transporter family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5RKL7.1 GenPept UniProtKB/Swiss-Prot:Q5RKL7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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