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    Sugp1 SURP and G patch domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 290666, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sugp1provided by RGD
    Official Full Name
    SURP and G patch domain containing 1provided by RGD
    Primary source
    RGD:1310496
    See related
    EnsemblRapid:ENSRNOG00000052111 AllianceGenome:RGD:1310496
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Sf4
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Predicted to be active in nucleoplasm. Orthologous to human SUGP1 (SURP and G-patch domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 116.8), Adrenal (RPKM 105.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Sugp1 in Genome Data Viewer
    Location:
    16p14
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (19386588..19417460, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (19352659..19383533, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (21100923..21131795, complement)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene hyaluronan and proteoglycan link protein 4 Neighboring gene transmembrane 6 superfamily member 2 Neighboring gene MAU2 sister chromatid cohesion factor Neighboring gene GATA zinc finger domain containing 2A Neighboring gene testis-specific serine kinase 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    SURP and G-patch domain-containing protein 1
    Names
    splicing factor 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011920.1 → NP_001011920.1  SURP and G-patch domain-containing protein 1

      See identical proteins and their annotated locations for NP_001011920.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079341
      UniProtKB/Swiss-Prot
      Q68FU8
      UniProtKB/TrEMBL
      A0A8L2R876, A6KA93
      Related
      ENSRNOP00000082578.1, ENSRNOT00000110921.2
      Conserved Domains (2) summary
      pfam01585
      Location:562 → 606
      G-patch; G-patch domain
      pfam01805
      Location:187 → 238
      Surp; Surp module

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      19386588..19417460 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039094335.2 → XP_038950263.1  SURP and G-patch domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8L2R876
      Related
      ENSRNOP00000072874.2, ENSRNOT00000078005.3
      Conserved Domains (3) summary
      PHA02682
      Location:285 → 379
      PHA02682; ORF080 virion core protein; Provisional
      pfam01585
      Location:543 → 587
      G-patch; G-patch domain
      pfam01805
      Location:168 → 219
      Surp; Surp module
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q68FU8.1 GenPept UniProtKB/Swiss-Prot:Q68FU8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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