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    Tmem80 transmembrane protein 80 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309109, updated on 9-Dec-2024

    Summary

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    Symbol
    Tmem80provided by RGD
    Full Name
    transmembrane protein 80provided by RGD
    Primary source
    RGD:1308399
    See related
    EnsemblRapid:ENSRNOG00000063852 AllianceGenome:RGD:1308399
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308399
    Summary
    Predicted to be involved in non-motile cilium assembly. Predicted to be located in membrane. Predicted to be active in ciliary transition zone. Orthologous to human TMEM80 (transmembrane protein 80). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 76.2), Adrenal (RPKM 75.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem80 in Genome Data Viewer
    Location:
    1q41
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (205865564..205873933)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (196435999..196444368)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (214317300..214326293)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene dopamine receptor D4 Neighboring gene DEAF1 transcription factor Neighboring gene EPS8-like 2 Neighboring gene transaldolase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone. Li C, et al. PLoS Biol, 2016 Mar. PMID 26982032, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in ciliary transition zone ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 80

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001402263.1 → NP_001389192.1  transmembrane protein 80 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6HXU3, A6HXU4
      Related
      ENSRNOP00000100554.1, ENSRNOT00000127787.1

    2. NM_001402264.1 → NP_001389193.1  transmembrane protein 80 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      Q5XID3
      Related
      ENSRNOP00000106129.1, ENSRNOT00000147130.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      205865564..205873933
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001017455.1: Suppressed sequence

      Description
      NM_001017455.1: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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