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    ORC6 origin recognition complex protein 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839227, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ORC6
    Official Full Name
    origin recognition complex protein 6
    Primary source
    TAIR:AT1G26840
    Locus tag
    AT1G26840
    See related
    Araport:AT1G26840
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6; ATORC6; origin recognition complex protein 6; ORIGIN RECOGNITION COMPLEX SUBUNIT 6; T2P11.3; T2P11_3
    Summary
    Origin Recognition Complex subunit 6. Involved in the initiation of DNA replication. Regulated transcriptionally during cell cycle, peaking at G1/S-phase. Target of E2F/DF family of transcription factors.
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    Genomic context

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    See ORC6 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (9298670..9300800)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ribonuclease 3 Neighboring gene cullin 3 Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis transcription factor IIB-related protein BRP4 is involved in the regulation of mitotic cell-cycle progression during male gametogenesis. Qin Z, et al. J Exp Bot, 2014 Jun. PMID 24723406, Free PMC Article
    2. The genes encoding Arabidopsis ORC subunits are E2F targets and the two ORC1 genes are differently expressed in proliferating and endoreplicating cells. Diaz-Trivino S, et al. Nucleic Acids Res, 2005. PMID 16179646, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_102448.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA replication ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nuclear origin of replication recognition complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    part_of origin recognition complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    origin recognition complex protein 6
    NP_174006.2
    • origin recognition complex protein 6 (ORC6); FUNCTIONS IN: DNA binding; INVOLVED IN: DNA replication; LOCATED IN: origin recognition complex; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Origin recognition complex, subunit 6, metazoa/plant (InterPro:IPR020529), Origin recognition complex, subunit 6 (InterPro:IPR008721); Has 179 Blast hits to 179 proteins in 66 species: Archae - 0; Bacteria - 0; Metazoa - 105; Fungi - 0; Plants - 56; Viruses - 0; Other Eukaryotes - 18 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      9298670..9300800
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102448.4 → NP_174006.2  origin recognition complex protein 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174006.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6EWW9, Q9ZVH3
      UniProtKB/TrEMBL
      A0A178WC62, A0A5S9W3Q6, A0A654EDZ6
      Conserved Domains (2) summary
      cd11583
      Location:93 → 187
      Orc6_mid; Middle domain of the origin recognition complex subunit 6
      cl21687
      Location:3 → 92
      Orc6_mid; Middle domain of the origin recognition complex subunit 6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZVH3.2

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