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    AtNug2 GTP-binding family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841731, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AtNug2
    Official Full Name
    GTP-binding family protein
    Primary source
    TAIR:AT1G52980
    Locus tag
    AT1G52980
    See related
    Araport:AT1G52980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F14G24.25; F14G24_25; nuclear/nucleolar GTPase 2; Nug2
    Summary
    Encodes a GTPase that belongs to the subfamily of YlqF/YawG GTPases. Functions in Pre-60S ribosomal subunit maturation.
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    Genomic context

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    See AtNug2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (19737405..19740348)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene downregulated in DIF1 11 Neighboring gene thioredoxin family protein Neighboring gene Nucleotide-diphospho-sugar transferases superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nuclear/nucleolar GTPase 2 proteins as a subfamily of YlqF/YawG GTPases function in pre-60S ribosomal subunit maturation of mono- and dicotyledonous plants. Im CH, et al. J Biol Chem, 2011 Mar 11. PMID 21205822, Free PMC Article
    2. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_104176.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within ribosome biogenesis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    GTP-binding family protein
    NP_175706.1
    • GTP-binding family protein; FUNCTIONS IN: GTP binding; INVOLVED IN: biological_process unknown; LOCATED IN: intracellular; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GTP1/OBG (InterPro:IPR006073), GTP-binding protein, HSR1-related (InterPro:IPR002917), NGP1, N-terminal (InterPro:IPR012971); BEST Arabidopsis thaliana protein match is: GTP-binding family protein (TAIR:AT3G07050.1); Has 37841 Blast hits to 9407 proteins in 1963 species: Archae - 139; Bacteria - 33291; Metazoa - 1149; Fungi - 897; Plants - 387; Viruses - 125; Other Eukaryotes - 1853 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      19737405..19740348
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104176.4 → NP_175706.1  GTP-binding family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175706.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z385, Q9C923
      UniProtKB/TrEMBL
      A0A5S9WP90, A0A654EHZ4
      Conserved Domains (4) summary
      cd01858
      Location:208 → 364
      NGP_1; A novel nucleolar GTP-binding protein, circularly permuted subfamily of the Ras GTPases
      COG1161
      Location:199 → 484
      RbgA; Ribosome biogenesis GTPase A [Translation, ribosomal structure and biogenesis]
      pfam08153
      Location:44 → 169
      NGP1NT; NGP1NT (NUC091) domain
      cl01319
      Location:533 → 573
      HARE-HTH; HB1, ASXL, restriction endonuclease HTH domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C923.1

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