GAMMA CA1 gamma carbonic anhydrase 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: GAMMA CA1
Official Full Name: gamma carbonic anhydrase 1
Primary source: TAIR:AT1G19580
Locus tag: AT1G19580
See related: Araport:AT1G19580
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: gamma carbonic anhydrase 1
Summary: Encodes mitochondrial gamma carbonic anhydrase. Component of the NADH dehydrogenase complex.
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Genomic context

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See GAMMA CA1 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 6

Sequence:: Chromosome: 1; NC_003070.9 (6774683..6777568)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

At1g19580 is required for complex I assembly and that reproductive development is dependent on the presence of complex I.
Title: Mitochondrial gamma carbonic anhydrases are required for complex I assembly and plant reproductive development.
AT1G19580 contributes to sustaining efficient photosynthesis under ambient (photorespiratory) conditions.
Title: Functional characterization of mutants affected in the carbonic anhydrase domain of the respiratory complex I in Arabidopsis thaliana.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001198110.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
NOT enables carbonate dehydratase activity	ISS Inferred from Sequence or Structural Similarity more info
enables carbonate dehydratase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within photorespiration	TAS Traceable Author Statement more info	PubMed
involved_in protein homotrimerization	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in mitochondrial membrane	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	HDA more info	PubMed
part_of respiratory chain complex I	HDA more info	PubMed
part_of respiratory chain complex I	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: gamma carbonic anhydrase 1

NP_001185039.1

gamma carbonic anhydrase 1 (GAMMA CA1); CONTAINS InterPro DOMAIN/s: Trimeric LpxA-like (InterPro:IPR011004); BEST Arabidopsis thaliana protein match is: gamma carbonic anhydrase 3 (TAIR:AT5G66510.1).

NP_564091.1

gamma carbonic anhydrase 1 (GAMMA CA1); FUNCTIONS IN: carbonate dehydratase activity; INVOLVED IN: photorespiration; LOCATED IN: mitochondrion, mitochondrial membrane, mitochondrial respiratory chain complex I, respiratory chain complex I; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Trimeric LpxA-like (InterPro:IPR011004); BEST Arabidopsis thaliana protein match is: gamma carbonic anhydrase 2 (TAIR:AT1G47260.1); Has 10894 Blast hits to 10839 proteins in 2210 species: Archae - 265; Bacteria - 7962; Metazoa - 13; Fungi - 83; Plants - 197; Viruses - 0; Other Eukaryotes - 2374 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

6774683..6777568

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_101815.4 → NP_564091.1 gamma carbonic anhydrase 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_564091.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q67XH5, Q682H9, Q8LF67, Q9FWR5, Q9LN36

UniProtKB/TrEMBL

A0A178WHZ1, A0A5S9V4N8

Conserved Domains (1) summary

PLN02296
Location:1 → 269

PLN02296; carbonate dehydratase
NM_001198110.1 → NP_001185039.1 gamma carbonic anhydrase 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001185039.1

Status: REVIEWED

UniProtKB/TrEMBL

F4HP82

Conserved Domains (1) summary

cd04645
Location:55 → 179

LbH_gamma_CA_like; Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon ...