U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PRXIIF peroxiredoxin IIF [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819778, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PRXIIF
    Official Full Name
    peroxiredoxin IIF
    Primary source
    TAIR:AT3G06050
    Locus tag
    AT3G06050
    See related
    Araport:AT3G06050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPRXIIF; F24F17.3; F24F17_3; peroxiredoxin IIF; PEROXIREDOXIN IIF
    Summary
    Encodes a mitochondrial matrix localized peroxiredoxin involved in redox homeostasis. Knockout mutants have reduced root growth under certain oxidative stress conditions.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PRXIIF in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (1825999..1827917, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Glycoprotein membrane precursor GPI-anchored Neighboring gene Ribosomal protein L12/ ATP-dependent Clp protease adaptor protein ClpS family protein Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The mitochondrial type II peroxiredoxin F is essential for redox homeostasis and root growth of Arabidopsis thaliana under stress. Finkemeier I, et al. J Biol Chem, 2005 Apr 1. PMID 15632145
    2. The impact of oxidative stress on Arabidopsis mitochondria. Sweetlove LJ, et al. Plant J, 2002 Dec. PMID 12492832
    3. Heterogeneity of the mitochondrial proteome for photosynthetic and non-photosynthetic Arabidopsis metabolism. Lee CP, et al. Mol Cell Proteomics, 2008 Jul. PMID 18385124
    4. The Extra-Pathway Interactome of the TCA Cycle: Expected and Unexpected Metabolic Interactions. Zhang Y, et al. Plant Physiol, 2018 Jul. PMID 29794018, Free PMC Article
    5. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PrxII F has a role in antioxidant defense and possibly in redox signaling in plant cells [AtPrxII F (Peroxiredoxin II F)]
      Title: The mitochondrial type II peroxiredoxin F is essential for redox homeostasis and root growth of Arabidopsis thaliana under stress.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001337629.1
    NM_111480.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables peroxidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables thioredoxin peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in mitochondrial matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    peroxiredoxin IIF
    NP_566268.1
    • peroxiredoxin IIF (PRXIIF); FUNCTIONS IN: peroxidase activity, antioxidant activity; INVOLVED IN: response to oxidative stress, response to cadmium ion; LOCATED IN: mitochondrion, mitochondrial matrix; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336), Redoxin (InterPro:IPR013740); BEST Arabidopsis thaliana protein match is: Thioredoxin superfamily protein (TAIR:AT1G60740.1); Has 3925 Blast hits to 3925 proteins in 881 species: Archae - 6; Bacteria - 1549; Metazoa - 168; Fungi - 305; Plants - 221; Viruses - 0; Other Eukaryotes - 1676 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1825999..1827917 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111480.4 → NP_566268.1  peroxiredoxin IIF [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566268.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LEJ1, Q8LPM1, Q941C2, Q9M7T0
      UniProtKB/TrEMBL
      A0A178VBA5, A0A5S9X9U6, A0A654F4M5
      Conserved Domains (1) summary
      cd03013
      Location:67 → 198
      PRX5_like; Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5 ...

    2. NM_001337629.1 → NP_001327152.1  peroxiredoxin IIF [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LRF4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M7T0.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools