U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CML38 calmodulin-like 38 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843998, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CML38
    Official Full Name
    calmodulin-like 38
    Primary source
    TAIR:AT1G76650
    Locus tag
    AT1G76650
    See related
    Araport:AT1G76650
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    calmodulin-like 38; F28O16.2; F28O16_2
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CML38 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (28766750..28768138, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene Calcium-binding EF-hand family protein Neighboring gene hydroxyproline-rich glycoprotein family protein Neighboring gene Nucleotide-sugar transporter family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Arabidopsis CALMODULIN-LIKE 38 Regulates Hypoxia-Induced Autophagy of SUPPRESSOR OF GENE SILENCING 3 Bodies. Field S, et al. Front Plant Sci, 2021. PMID 34567037, Free PMC Article
    2. Arabidopsis CML38, a Calcium Sensor That Localizes to Ribonucleoprotein Complexes under Hypoxia Stress. Lokdarshi A, et al. Plant Physiol, 2016 Feb. PMID 26634999, Free PMC Article
    3. CALMODULIN-LIKE-38 and PEP1 RECEPTOR 2 integrate nitrate and brassinosteroid signals to regulate root growth. Song X, et al. Plant Physiol, 2021 Nov 3. PMID 34618046, Free PMC Article
    4. Arabidopsis thaliana rapid alkalinization factor 1-mediated root growth inhibition is dependent on calmodulin-like protein 38. Campos WF, et al. J Biol Chem, 2018 Feb 9. PMID 29282286, Free PMC Article
    5. Developmental and stimulus-induced expression patterns of Arabidopsis calmodulin-like genes CML37, CML38 and CML39. Vanderbeld B, et al. Plant Mol Biol, 2007 Aug. PMID 17579812

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CALMODULIN-LIKE-38 and PEP1 RECEPTOR 2 integrate nitrate and brassinosteroid signals to regulate root growth.
      Title: CALMODULIN-LIKE-38 and PEP1 RECEPTOR 2 integrate nitrate and brassinosteroid signals to regulate root growth.
    2. a new component of the AtRALF1 response pathway is a calmodulin-like protein that binds AtRALF1, is essential for root growth inhibition, and has no role in AtRALF1 alkalinization.
      Title: Arabidopsis thaliana rapid alkalinization factor 1-mediated root growth inhibition is dependent on calmodulin-like protein 38.
    3. CML38 is a core hypoxia response calcium sensor protein.
      Title: Arabidopsis CML38, a Calcium Sensor That Localizes to Ribonucleoprotein Complexes under Hypoxia Stress.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001084365.1
    NM_001198484.1
    NM_106315.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables signaling receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    involved_in nitrate assimilation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of brassinosteroid mediated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in response to hypoxia IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to wounding IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    calmodulin-like 38
    NP_001077834.1
    • calmodulin-like 38 (CML38); FUNCTIONS IN: calcium ion binding; INVOLVED IN: response to wounding; LOCATED IN: plasma membrane; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 (InterPro:IPR018249), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048); BEST Arabidopsis thaliana protein match is: Calcium-binding EF-hand family protein (TAIR:AT1G76640.1); Has 9270 Blast hits to 8846 proteins in 1061 species: Archae - 0; Bacteria - 21; Metazoa - 3654; Fungi - 1209; Plants - 2975; Viruses - 0; Other Eukaryotes - 1411 (source: NCBI BLink).
    NP_001185413.1
    • calmodulin-like 38 (CML38); CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 (InterPro:IPR018249), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048); BEST Arabidopsis thaliana protein match is: Calcium-binding EF-hand family protein (TAIR:AT1G76640.1).
    NP_177791.1
    • calmodulin-like 38 (CML38); FUNCTIONS IN: calcium ion binding; INVOLVED IN: response to wounding; LOCATED IN: plasma membrane; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 (InterPro:IPR018249), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand-like domain (InterPro:IPR011992); BEST Arabidopsis thaliana protein match is: Calcium-binding EF-hand family protein (TAIR:AT1G76640.1); Has 14301 Blast hits to 11244 proteins in 1181 species: Archae - 0; Bacteria - 48; Metazoa - 5820; Fungi - 2427; Plants - 3932; Viruses - 0; Other Eukaryotes - 2074 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      28766750..28768138 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106315.3 → NP_177791.1  calmodulin-like 38 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177791.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MQS8, Q8LBV6, Q9SRE6
      UniProtKB/TrEMBL
      A0A178WMC5, A0A5S9WUX2
      Conserved Domains (1) summary
      PTZ00183
      Location:38 → 177
      PTZ00183; centrin; Provisional

    2. NM_001084365.1 → NP_001077834.1  calmodulin-like 38 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077834.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9WUX2
      Conserved Domains (2) summary
      PTZ00184
      Location:38 → 166
      PTZ00184; calmodulin; Provisional
      cd00051
      Location:43 → 95
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    3. NM_001198484.1 → NP_001185413.1  calmodulin-like 38 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185413.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MQS8, Q8LBV6, Q9SRE6
      UniProtKB/TrEMBL
      A0A178WMC5, A0A5S9WUX2
      Conserved Domains (1) summary
      PTZ00183
      Location:38 → 177
      PTZ00183; centrin; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SRE6.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.