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    GLCAK glucuronokinase G [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819902, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GLCAK
    Official Full Name
    glucuronokinase G
    Primary source
    TAIR:AT3G01640
    Locus tag
    AT3G01640
    See related
    Araport:AT3G01640
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA GLUCURONOKINASE; ATGLCAK; F4P13.18; F4P13_18; glucuronokinase G
    Summary
    AtGlcAK is a sugar kinase able to phosphorylate D-GlcA to D-GlcA-1-phosphate in the presence of ATP.
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    Genomic context

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    See GLCAK in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (239333..241492)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene beta-1,4-N-acetylglucosaminyltransferase family protein Neighboring gene ncRNA Neighboring gene Major facilitator superfamily protein Neighboring gene RING domain ligase1 Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning of Glucuronokinase from Arabidopsis thaliana, the last missing enzyme of the myo-inositol oxygenase pathway to nucleotide sugars. Pieslinger AM, et al. J Biol Chem, 2010 Jan 29. PMID 19951951, Free PMC Article
    2. Identification of proteins expressed at extremely low level in Arabidopsis leaves. Xu Y, et al. Biochem Biophys Res Commun, 2007 Jul 6. PMID 17511964
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Glucuronokinase in Arabidopsis thaliana is an enzyme of the myo-inositol oxygenase pathway
      Title: Cloning of Glucuronokinase from Arabidopsis thaliana, the last missing enzyme of the myo-inositol oxygenase pathway to nucleotide sugars.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_111030.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    NOT enables L-arabinokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT enables galactokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT enables galacturonokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT enables glucokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glucuronokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables poly(U) RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell wall biogenesis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within inositol metabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen tube development TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    glucuronokinase G
    NP_566144.2
    • glucuronokinase G (GLCAK); FUNCTIONS IN: poly(U) RNA binding, glucuronokinase activity, ATP binding; INVOLVED IN: cell wall biogenesis, inositol metabolic process, pollen tube development; LOCATED IN: cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Mevalonate/galactokinase (InterPro:IPR006206), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), GHMP kinase (InterPro:IPR006204), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721), GHMP kinase, C-terminal (InterPro:IPR013750); BEST Arabidopsis thaliana protein match is: GHMP kinase family protein (TAIR:AT5G14470.1); Has 420 Blast hits to 420 proteins in 152 species: Archae - 38; Bacteria - 195; Metazoa - 13; Fungi - 2; Plants - 68; Viruses - 0; Other Eukaryotes - 104 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      239333..241492
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001337351.1 → NP_001327199.1  glucuronokinase G [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VL41, A0A1I9LRK4, A0A5S9X8A6

    2. NM_111030.3 → NP_566144.2  glucuronokinase G [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566144.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93ZC9, Q9SS91
      UniProtKB/TrEMBL
      A0A178VL41, A0A5S9X8A6
      Conserved Domains (1) summary
      cl40722
      Location:20 → 349
      COG2605; Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93ZC9.1

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