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    NPY5 Phototropic-responsive NPH3 family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829914, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NPY5
    Official Full Name
    Phototropic-responsive NPH3 family protein
    Primary source
    TAIR:AT4G37590
    Locus tag
    AT4G37590
    See related
    Araport:AT4G37590
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F19F18.80; F19F18_80; MAB4/ENP/NPY1-LIKE 1; MEL1; NAKED PINS IN YUC MUTANTS 5
    Summary
    A member of the NPY gene family (NPY1/AT4G31820, NPY2/AT2G14820, NPY3/AT5G67440, NPY4/AT2G23050, NPY5/AT4G37590). Involved in auxin-mediated organogenesis.
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    Genomic context

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    See NPY5 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (17662840..17666736, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Acyl-CoA N-acyltransferases (NAT) superfamily protein Neighboring gene uncharacterized protein Neighboring gene BTB and TAZ domain protein 5 Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MAB4-induced auxin sink generates local auxin gradients in Arabidopsis organ formation. Furutani M, et al. Proc Natl Acad Sci U S A, 2014 Jan 21. PMID 24395791, Free PMC Article
    2. Polar-localized NPH3-like proteins regulate polarity and endocytosis of PIN-FORMED auxin efflux carriers. Furutani M, et al. Development, 2011 May. PMID 21490067
    3. AGC kinases and MAB4/MEL proteins maintain PIN polarity by limiting lateral diffusion in plant cells. Glanc M, et al. Curr Biol, 2021 May 10. PMID 33705718, Free PMC Article
    4. NPY genes and AGC kinases define two key steps in auxin-mediated organogenesis in Arabidopsis. Cheng Y, et al. Proc Natl Acad Sci U S A, 2008 Dec 30. PMID 19075219, Free PMC Article
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_119923.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to auxin stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within flower development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within positive gravitropism IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in positive regulation of flower development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein localization involved in auxin polar transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of auxin polar transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Phototropic-responsive NPH3 family protein
    NP_568030.1
    • NAKED PINS IN YUC MUTANTS 5 (NPY5); FUNCTIONS IN: signal transducer activity; INVOLVED IN: flower development, response to light stimulus; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NPH3 (InterPro:IPR004249), BTB/POZ (InterPro:IPR013069), BTB/POZ fold (InterPro:IPR011333), BTB/POZ-like (InterPro:IPR000210); BEST Arabidopsis thaliana protein match is: Phototropic-responsive NPH3 family protein (TAIR:AT2G23050.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      17662840..17666736 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119923.4 → NP_568030.1  Phototropic-responsive NPH3 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568030.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JS42, Q0WL52, Q940F9, Q9SZF2
      UniProtKB/TrEMBL
      A0A178V267
      Conserved Domains (1) summary
      pfam03000
      Location:214 → 441
      NPH3; NPH3 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0WL52.2

    Gene LinkOut

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