U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FTSZ2-2 Tubulin/FtsZ family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824441, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FTSZ2-2
    Official Full Name
    Tubulin/FtsZ family protein
    Primary source
    TAIR:AT3G52750
    Locus tag
    AT3G52750
    See related
    Araport:AT3G52750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Summary
    Nuclear gene that encodes a plastidial division protein (FtsZ2-2). FtsZ2-2 is involved in chloroplast morphology and internal organisation in addition to participating in chloroplast partition
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FTSZ2-2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (19549604..19553136, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Integral membrane Yip1 family protein Neighboring gene tRNA-Asp

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Multiple FtsZ2 isoforms involved in chloroplast division and biogenesis are developmentally associated with thylakoid membranes in Arabidopsis. Karamoko M, et al. FEBS Lett, 2011 Apr 20. PMID 21439281
    2. Chloroplast targeting of chloroplast division FtsZ2 proteins in Arabidopsis. Fujiwara M, et al. Biochem Biophys Res Commun, 2001 Sep 21. PMID 11554751
    3. GTP-dependent heteropolymer formation and bundling of chloroplast FtsZ1 and FtsZ2. Olson BJ, et al. J Biol Chem, 2010 Jul 2. PMID 20421292, Free PMC Article
    4. Arabidopsis FtsZ2-1 and FtsZ2-2 are functionally redundant, but FtsZ-based plastid division is not essential for chloroplast partitioning or plant growth and development. Schmitz AJ, et al. Mol Plant, 2009 Nov. PMID 19995726
    5. Colocalization of plastid division proteins in the chloroplast stromal compartment establishes a new functional relationship between FtsZ1 and FtsZ2 in higher plants. McAndrew RS, et al. Plant Physiol, 2001 Dec. PMID 11743110, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results suggest that ARC3 directly inhibits Z-ring assembly through interaction with FtsZ2 in heteropolymers and that ARC3 activity is spatially regulated by MinD1 and MinE1 to permit Z-ring assembly at the mid-plastid.
      Title: Chloroplast division protein ARC3 regulates chloroplast FtsZ-ring assembly and positioning in arabidopsis through interaction with FtsZ2.
    2. AtFtsZ2 is phosphorylated in vivo in Arabidopsis and that PGK1 (phosphoglycerate kinase 1) interacts with AtFtsZ2 in planta, suggesting a possible role in FtsZ phosphorylation.
      Title: In vivo phosphorylation of FtsZ2 in Arabidopsis thaliana.
    3. Data show that FtsZ2-1 is essential for chloroplast division and that FtsZ2-2 plays a specific role in chloroplast morphology and internal organisation in addition to participating in chloroplast partition.
      Title: Multiple FtsZ2 isoforms involved in chloroplast division and biogenesis are developmentally associated with thylakoid membranes in Arabidopsis.
    4. Evolution of FtsZ-2 in green plants, perhaps arising from an enhanced capacity for the regulation of Z ring composition and activity in vivo.
      Title: GTP-dependent heteropolymer formation and bundling of chloroplast FtsZ1 and FtsZ2.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001339587.1
    NM_001339588.1
    NM_115135.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chloroplast fission IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast thylakoid HDA PubMed 
    colocalizes_with chloroplast thylakoid membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in contractile ring IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in plastid stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in thylakoid membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Tubulin/FtsZ family protein
    NP_190843.1
    • FTSZ2-2; FUNCTIONS IN: structural molecule activity, GTP binding, GTPase activity; INVOLVED IN: protein polymerization; LOCATED IN: chloroplast stroma, chloroplast, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cell division protein FtsZ, N-terminal (InterPro:IPR000158), Cell division protein FtsZ, conserved site (InterPro:IPR020805), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: Tubulin/FtsZ family protein (TAIR:AT2G36250.2); Has 10464 Blast hits to 10464 proteins in 3156 species: Archae - 455; Bacteria - 6195; Metazoa - 8; Fungi - 0; Plants - 153; Viruses - 0; Other Eukaryotes - 3653 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19549604..19553136 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001339586.1 → NP_001327517.1  Tubulin/FtsZ family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93ZQ7, Q9LXJ0
      UniProtKB/TrEMBL
      A0A178V810, A0A654FF86
      Conserved Domains (1) summary
      PRK09330
      Location:101 → 465
      PRK09330; cell division protein FtsZ; Validated

    2. NM_115135.3 → NP_190843.1  Tubulin/FtsZ family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190843.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93ZQ7, Q9LXJ0
      UniProtKB/TrEMBL
      A0A178V810, A0A654FF86
      Conserved Domains (1) summary
      PRK09330
      Location:101 → 465
      PRK09330; cell division protein FtsZ; Validated

    3. NM_001339587.1 → NP_001327516.1  Tubulin/FtsZ family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93ZQ7, Q9LXJ0
      UniProtKB/TrEMBL
      A0A178V810, A0A654FF86
      Conserved Domains (1) summary
      PRK09330
      Location:101 → 465
      PRK09330; cell division protein FtsZ; Validated

    4. NM_001339588.1 → NP_001327515.1  Tubulin/FtsZ family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LSJ8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LXJ0.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools