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    N2,N2-dimethylguanosine tRNA methyltransferase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824800, updated on 18-Sep-2024

    Summary

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    Official Full Name
    N2,N2-dimethylguanosine tRNA methyltransferase
    Primary source
    TAIR:AT3G56330
    Locus tag
    AT3G56330
    See related
    Araport:AT3G56330
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T5P19.2
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (20890235..20892002)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Melibiase family protein Neighboring gene ncRNA Neighboring gene PAP/OAS1 substrate-binding domain superfamily Neighboring gene Ribosomal protein S26e family protein Neighboring gene Iron/manganese superoxide dismutase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of the enzymes responsible for m2,2G and acp3U formation on cytosolic tRNA from insects and plants. Funk HM, et al. PLoS One, 2020. PMID 33253256, Free PMC Article
    2. In-depth temporal transcriptome profiling reveals a crucial developmental switch with roles for RNA processing and organelle metabolism that are essential for germination in Arabidopsis. Narsai R, et al. Plant Physiol, 2011 Nov. PMID 21908688, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_115491.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables tRNA (guanine(10)-N2)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA (guanine(26)-N2)-dimethyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within tRNA modification IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    N2,N2-dimethylguanosine tRNA methyltransferase
    NP_191192.1
    • N2,N2-dimethylguanosine tRNA methyltransferase; FUNCTIONS IN: RNA binding, tRNA (guanine-N2-)-methyltransferase activity; INVOLVED IN: tRNA processing; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: N2,N2-dimethylguanosine tRNA methyltransferase (InterPro:IPR002905); BEST Arabidopsis thaliana protein match is: N2,N2-dimethylguanosine tRNA methyltransferase (TAIR:AT5G15810.1); Has 951 Blast hits to 937 proteins in 347 species: Archae - 257; Bacteria - 66; Metazoa - 191; Fungi - 140; Plants - 103; Viruses - 0; Other Eukaryotes - 194 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      20890235..20892002
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115491.4 → NP_191192.1  N2,N2-dimethylguanosine tRNA methyltransferase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191192.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V8D3, A0A5S9XLB8, A0A7G2EY93, Q9LYL0
      Conserved Domains (1) summary
      cl17173
      Location:73 → 432
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version

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