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    OXP1 oxoprolinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833761, updated on 18-Sep-2024

    Summary

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    Official Symbol
    OXP1
    Official Full Name
    oxoprolinase 1
    Primary source
    TAIR:AT5G37830
    Locus tag
    AT5G37830
    See related
    Araport:AT5G37830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K22F20.70; K22F20_70; oxoprolinase 1
    Summary
    Encodes a 5-oxoprolinase that acts in the glutathione degradation pathway and in 5-oxoproline metabolism.
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    Genomic context

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    See OXP1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (15056188..15060866, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene NOD26-like intrinsic protein 4;1 Neighboring gene NOD26-like intrinsic protein 4;2 Neighboring gene plastid movement impaired protein Neighboring gene pfkB-like carbohydrate kinase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A gamma-glutamyl transpeptidase-independent pathway of glutathione catabolism to glutamate via 5-oxoproline in Arabidopsis. Ohkama-Ohtsu N, et al. Plant Physiol, 2008 Nov. PMID 18768907, Free PMC Article
    2. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
    3. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    4. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_123142.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 5-oxoprolinase (ATP-hydrolyzing) activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within glutathione catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in plasmodesma HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    oxoprolinase 1
    NP_198599.1
    • oxoprolinase 1 (OXP1); CONTAINS InterPro DOMAIN/s: Hydantoinase B/oxoprolinase (InterPro:IPR003692), Hydantoinase/oxoprolinase (InterPro:IPR002821), Hydantoinaseoxoprolinase, N-terminal (InterPro:IPR008040); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      15056188..15060866 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123142.5 → NP_198599.1  oxoprolinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198599.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WQ06, Q9FIZ7
      UniProtKB/TrEMBL
      A0A5S9Y8X1
      Conserved Domains (4) summary
      PLN02666
      Location:1 → 1266
      PLN02666; 5-oxoprolinase
      pfam01968
      Location:235 → 534
      Hydantoinase_A; Hydantoinase/oxoprolinase
      pfam02538
      Location:736 → 1263
      Hydantoinase_B; Hydantoinase B/oxoprolinase
      pfam05378
      Location:10 → 216
      Hydant_A_N; Hydantoinase/oxoprolinase N-terminal region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FIZ7.1

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