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    TSBtype2 tryptophan synthase beta type 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833841, updated on 18-Sep-2024

    Summary

    Official Symbol
    TSBtype2
    Official Full Name
    tryptophan synthase beta type 2
    Primary source
    TAIR:AT5G38530
    Locus tag
    AT5G38530
    See related
    Araport:AT5G38530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MBB18.6; MBB18_6; tryptophan synthase beta type 2
    Summary
    TSBtype2 encodes a type 2 tryptophan synthase beta subunit that catalyzes a condensation reaction between serine and indole to generate tryptophan.It appears to form a homodimer. Its biological role has not yet been determined, but it has a very high affinity for indole which may be involved in allowing TSBtype2 to carefully limit free indole build-up. But, to date no overall change in plant morphology or seedling root growth have been observed in tsbtype2 mutants, indicating that this gene is not essential under optimum conditions. n most organs, TSBtype2 is transcripts are expressed at a lower level than TSB1 but in dry seeds they are expressed at comparable levels.
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    Genomic context

    See TSBtype2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (15423980..15426576)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Rhomboid-related intramembrane serine protease family protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene Mannose-binding lectin superfamily protein Neighboring gene Mannose-binding lectin superfamily protein Neighboring gene Protein kinase superfamily protein

    Interactions

    General gene information

    NM_123214.5

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in chloroplast  
    located_in cytosol PubMed 

    General protein information

    Preferred Names
    tryptophan synthase beta type 2
    NP_198669.1
    • tryptophan synthase beta type 2 (TSBtype2); FUNCTIONS IN: pyridoxal phosphate binding, tryptophan synthase activity, catalytic activity; INVOLVED IN: tryptophan biosynthetic process, metabolic process; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent enzyme, beta subunit (InterPro:IPR001926), Tryptophan synthase, beta chain-like (InterPro:IPR006316); BEST Arabidopsis thaliana protein match is: tryptophan synthase beta-subunit 2 (TAIR:AT4G27070.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      15423980..15426576
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123214.5NP_198669.1  tryptophan synthase beta type 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198669.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UFQ0, A0A5S9YA49, A0A654G6K9, Q9FFW8
      Conserved Domains (2) summary
      PRK12391
      Location:66483
      PRK12391; tryptophan synthase subunit beta; Reviewed
      pfam00291
      Location:127468
      PALP; Pyridoxal-phosphate dependent enzyme
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