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    XYLT beta-1,2-xylosyltransferase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835643, updated on 18-Sep-2024

    Summary

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    Official Symbol
    XYLT
    Official Full Name
    beta-1,2-xylosyltransferase
    Primary source
    TAIR:AT5G55500
    Locus tag
    AT5G55500
    See related
    Araport:AT5G55500
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''beta-1; 2-xylosyltransferase; 2-XYLOSYLTRANSFERASE; 2-xylosyltransferase''; ARABIDOPSIS THALIANA BETA-1; ATXYLT; beta-1
    Summary
    Encodes a beta-1,2-xylosyltransferase that is glycosylated at two positions.
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    Genomic context

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    See XYLT in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (22482125..22484631)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene gamete expressed protein 1 Neighboring gene tRNA-Ala Neighboring gene hydroxyproline-rich glycoprotein family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis thaliana beta1,2-xylosyltransferase: an unusual glycosyltransferase with the potential to act at multiple stages of the plant N-glycosylation pathway. Bencúr P, et al. Biochem J, 2005 Jun 1. PMID 15686448, Free PMC Article
    2. Structural requirements for Arabidopsis beta1,2-xylosyltransferase activity and targeting to the Golgi. Pagny S, et al. Plant J, 2003 Jan. PMID 12943552
    3. The Golgi localization of Arabidopsis thaliana beta1,2-xylosyltransferase in plant cells is dependent on its cytoplasmic and transmembrane sequences. Dirnberger D, et al. Plant Mol Biol, 2002 Sep. PMID 12175019
    4. Molecular cloning and functional expression of beta1, 2-xylosyltransferase cDNA from Arabidopsis thaliana. Strasser R, et al. FEBS Lett, 2000 Apr 21. PMID 10781814
    5. An antibody produced in tobacco expressing a hybrid beta-1,4-galactosyltransferase is essentially devoid of plant carbohydrate epitopes. Bakker H, et al. Proc Natl Acad Sci U S A, 2006 May 16. PMID 16675551, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtXYLT acts on protein-bound N-glycans prior to alpha1,3-fucosyltransferase and mannosidase II.
      Title: Arabidopsis β1,2-xylosyltransferase: substrate specificity and participation in the plant-specific N-glycosylation pathway.
    2. The substrate specificity of XylT permits the enzyme to act at multiple stages of the plant N-glycosylation pathway.
      Title: Arabidopsis thaliana beta1,2-xylosyltransferase: an unusual glycosyltransferase with the potential to act at multiple stages of the plant N-glycosylation pathway.
    3. Data show that expression of a hybrid enzyme of Arabidopsis thaliana xylosyltransferase and human beta-1,4-galactosyltransferase I in tobacco causes a reduction of N-glycans with potentially immunogenic core-bound xylose and fucose residues.
      Title: An antibody produced in tobacco expressing a hybrid beta-1,4-galactosyltransferase is essentially devoid of plant carbohydrate epitopes.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_124932.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glycoprotein 2-beta-D-xylosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables xylosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within post-translational protein targeting to membrane, translocation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within protein N-linked glycosylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in Golgi medial cisterna IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in Golgi trans cisterna HDA PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    beta-1,2-xylosyltransferase
    NP_568825.1
    • ''beta-1,2-xylosyltransferase'' (XYLT); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      22482125..22484631
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124932.4 → NP_568825.1  beta-1,2-xylosyltransferase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568825.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LDH0, Q9LKK7
      UniProtKB/TrEMBL
      A0A5S9YFE5, W8PUA9
      Conserved Domains (1) summary
      pfam04577
      Location:248 → 513
      DUF563; Protein of unknown function (DUF563)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LDH0.1

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