U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    RPT3 regulatory particle triple-A ATPase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835941, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    RPT3
    Official Full Name
    regulatory particle triple-A ATPase 3
    Primary source
    TAIR:AT5G58290
    Locus tag
    AT5G58290
    See related
    Araport:AT5G58290
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    26S PROTEASOME AAA-ATPASE SUBUNIT RPT3; MCK7.16; MCK7_16; regulatory particle triple-A ATPase 3
    Summary
    26S proteasome AAA-ATPase subunit RPT3 (RPT3) mRNA
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See RPT3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (23569052..23571854)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene oxidoreductases, acting on NADH or NADPH, quinone or similar compound as acceptor Neighboring gene ABC transporter of the mitochondrion 3 Neighboring gene AP2/B3-like transcriptional factor family protein Neighboring gene Leucine-rich repeat protein kinase family protein Neighboring gene ncRNA Neighboring gene methyl esterase 18 Neighboring gene ncRNA Neighboring gene Kinase interacting (KIP1-like) family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A mutation in the Proteosomal Regulatory Particle AAA-ATPase-3 in Arabidopsis impairs the light-specific hypocotyl elongation response elicited by a glutamate receptor agonist, BMAA. Brenner ED, et al. Plant Mol Biol, 2009 Jul. PMID 19412571
    2. Proteomics analysis reveals a highly heterogeneous proteasome composition and the post-translational regulation of peptidase activity under pathogen signaling in plants. Sun HH, et al. J Proteome Res, 2013 Nov 1. PMID 23991809
    3. Structural and functional analysis of the six regulatory particle triple-A ATPase subunits from the Arabidopsis 26S proteasome. Fu H, et al. Plant J, 1999 Jun. PMID 10417703
    4. A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Glickman MH, et al. Cell, 1998 Sep 4. PMID 9741626
    5. Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome. Fu H, et al. EMBO J, 2001 Dec 17. PMID 11742986, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The mutation in bim409 was identified to be in a gene encoding the Proteosomal Regulatory Particle AAA-ATPase-3 (RPT3).
      Title: A mutation in the Proteosomal Regulatory Particle AAA-ATPase-3 in Arabidopsis impairs the light-specific hypocotyl elongation response elicited by a glutamate receptor agonist, BMAA.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_125214.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in plant-type cell wall HDA PubMed 
    located_in plasmodesma HDA PubMed 
    part_of proteasome complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proteasome regulatory particle, base subcomplex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    regulatory particle triple-A ATPase 3
    NP_200637.1
    • regulatory particle triple-A ATPase 3 (RPT3); FUNCTIONS IN: ATPase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome regulatory particle, base subcomplex, proteasome complex, cell wall, nucleus, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA-type, conserved site (InterPro:IPR003960), 26S proteasome subunit P45 (InterPro:IPR005937); BEST Arabidopsis thaliana protein match is: regulatory particle AAA-ATPase 2A (TAIR:AT4G29040.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      23569052..23571854
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125214.6 → NP_200637.1  regulatory particle triple-A ATPase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200637.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5PNS4, Q9SEI4
      UniProtKB/TrEMBL
      A0A178UAH2, A0A5S9YHH8, A0A7G2FH31
      Conserved Domains (1) summary
      PTZ00454
      Location:15 → 408
      PTZ00454; 26S protease regulatory subunit 6B-like protein; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SEI4.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools