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    CG44008 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 14462750, updated on 4-Jan-2025

    Summary

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    Official Symbol
    CG44008provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0264750
    Locus tag
    Dmel_CG44008
    See related
    AllianceGenome:FB:FBgn0264750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG31758; CG42325; Dmel\CG44008
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Involved in sexual reproduction. Located in extracellular space. [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See CG44008 in Genome Data Viewer
    Location:
    33A3-33A3; 2-45 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (11841502..11842445, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (11841502..11842445, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Phosphodiesterase 1c Neighboring gene antisense RNA:CR43936 Neighboring gene Seminal fluid protein 33A3 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Maltase B1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila soluble guanylyl cyclase mutants exhibit increased foraging locomotion: behavioral and genomic investigations. Riedl CA, et al. Behav Genet, 2005 May. PMID 15864439
    2. Integrated analysis of the aging brain transcriptome and proteome in tauopathy. Mangleburg CG, et al. Mol Neurodegener, 2020 Sep 29. PMID 32993812, Free PMC Article
    3. Drosophila microbiota modulates host metabolic gene expression via IMD/NF-κB signaling. Erkosar B, et al. PLoS One, 2014. PMID 24733183, Free PMC Article
    4. Endogenously imprinted genes in Drosophila melanogaster. McEachern LA, et al. Mol Genet Genomics, 2014 Aug. PMID 24658702
    5. Proteomics reveals novel Drosophila seminal fluid proteins transferred at mating. Findlay GD, et al. PLoS Biol, 2008 Jul 29. PMID 18666829, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in sexual reproduction HEP PubMed 
    Component Evidence Code Pubs
    located_in extracellular space HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG44008-PA
    CG44008-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      11841502..11842445 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273469.1 → NP_001260398.1  uncharacterized protein Dmel_CG44008, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260398.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PBA3
      Conserved Domains (1) summary
      cd00104
      Location:36 → 79
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...

    2. NM_001298922.1 → NP_001285851.1  uncharacterized protein Dmel_CG44008, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285851.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PBA3
      Conserved Domains (1) summary
      cd00104
      Location:36 → 79
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PBA3 M9PBA3

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