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    CG4882 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37787, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4882provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0025336
    Locus tag
    Dmel_CG4882
    See related
    AllianceGenome:FB:FBgn0025336
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-60Aa; Dmel\CG4882; GM14313; LD24471; UD1
    Summary
    Predicted to enable mitochondrial ribosome binding activity. Predicted to be involved in positive regulation of mitochondrial translation. Predicted to be part of mitochondrial small ribosomal subunit. Predicted to be active in mitochondrion. Is expressed in several structures, including adult head; adult heart; embryonic/larval midgut primordium; larval muscle cell; and mesoderm. Orthologous to human MRPS27 (mitochondrial ribosomal protein S27). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4882 in Genome Data Viewer
    Location:
    60A7-60A7; 2-105 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23880817..23882927, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19768340..19770450, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Mitochondrial trifunctional protein beta subunit Neighboring gene ken and barbie Neighboring gene Transmembrane 4 superfamily Neighboring gene Putative homeodomain protein Neighboring gene uncharacterized protein Neighboring gene Decapping protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The ken and barbie gene encoding a putative transcription factor with a BTB domain and three zinc finger motifs functions in terminalia development of Drosophila. Lukacsovich T, et al. Arch Insect Biochem Physiol, 2003 Oct. PMID 14518006
    2. Natural variation in sugar tolerance associates with changes in signaling and mitochondrial ribosome biogenesis. Melvin RG, et al. Elife, 2018 Nov 27. PMID 30480548, Free PMC Article
    3. The Drosophila melanogaster 60A chromosomal division is extremely dense with functional genes: their sequences, genomic organization, and expression. Lukacsovich T, et al. Genomics, 1999 Apr 1. PMID 10191082
    4. The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication. Zhang Y, et al. EMBO J, 2016 May 17. PMID 27053724, Free PMC Article
    5. Akirin specifies NF-κB selectivity of Drosophila innate immune response via chromatin remodeling. Bonnay F, et al. EMBO J, 2014 Oct 16. PMID 25180232, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables mitochondrial ribosome binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of mitochondrial translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4882-PA
    CG4882-PB
    undefined 1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23880817..23882927 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299862.1 → NP_001286791.1  uncharacterized protein Dmel_CG4882, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286791.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O77477
      Conserved Domains (1) summary
      pfam10037
      Location:1 → 350
      MRP-S27; Mitochondrial 28S ribosomal protein S27

    2. NM_058029.4 → NP_477377.1  uncharacterized protein Dmel_CG4882, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477377.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O77477
      Related
      FBpp0072134
      Conserved Domains (1) summary
      pfam10037
      Location:1 → 350
      MRP-S27; Mitochondrial 28S ribosomal protein S27
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O77477 O77477

    Gene LinkOut

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