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    mRpL48 mitochondrial ribosomal protein L48 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33348, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mRpL48provided by FlyBase
    Official Full Name
    mitochondrial ribosomal protein L48provided by FlyBase
    Primary source
    FLYBASE:FBgn0031357
    Locus tag
    Dmel_CG17642
    See related
    AllianceGenome:FB:FBgn0031357
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17642; Dmel\CG17642; MRP-L48
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in mitochondrial ribosome. Is expressed in several structures, including dorsal pharyngeal muscle primordium; embryonic/larval midgut; larval muscle cell; larval muscle system; and mesoderm. Orthologous to human MRPL48 (mitochondrial ribosomal protein L48). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mRpL48 in Genome Data Viewer
    Location:
    22B1-22B1; 2-3 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1710462..1711465)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1710462..1711465)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene capping protein beta Neighboring gene antisense RNA:CR44976 Neighboring gene uncharacterized protein Neighboring gene fritz Neighboring gene Replication in mitochondria 2 Neighboring gene Enolase Neighboring gene Ribosomal RNA processing 40

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The WD40 repeat protein fritz links cytoskeletal planar polarity to frizzled subcellular localization in the Drosophila epidermis. Collier S, et al. Genetics, 2005 Apr. PMID 15654087, Free PMC Article
    2. Centrobin controls mother-daughter centriole asymmetry in Drosophila neuroblasts. Januschke J, et al. Nat Cell Biol, 2013 Mar. PMID 23354166
    3. Retrotransposon-gene associations are widespread among D. melanogaster populations. Franchini LF, et al. Mol Biol Evol, 2004 Jul. PMID 15014149
    4. Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation. Garelli A, et al. Science, 2012 May 4. PMID 22556250
    5. Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogaster. Casad ME, et al. Genetics, 2011 Nov. PMID 21890737, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of mitochondrial large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    is_active_in mitochondrial ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial ribosomal protein L48
    Names
    CG17642-PA
    CG17642-PB
    mRpL48-PA
    mRpL48-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      1710462..1711465
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134769.3 → NP_608613.1  mitochondrial ribosomal protein L48, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608613.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQ35
      Related
      FBpp0077550
      Conserved Domains (1) summary
      pfam00338
      Location:50 → 144
      Ribosomal_S10; Ribosomal protein S10p/S20e

    2. NM_001272949.1 → NP_001259878.1  mitochondrial ribosomal protein L48, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259878.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQ35
      Conserved Domains (1) summary
      pfam00338
      Location:50 → 144
      Ribosomal_S10; Ribosomal protein S10p/S20e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQ35 Q9VQ35

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