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    Or47b Odorant receptor 47b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36212, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Or47bprovided by FlyBase
    Official Full Name
    Odorant receptor 47bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0026385
    Locus tag
    Dmel_CG13206
    See related
    AllianceGenome:FB:FBgn0026385
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    47b; 47E.2; CG13206; Dmel\CG13206; DmOr47b; DOR25; DOR47E.2; OR 47b; or47b; OR47b; Or47E.2
    Summary
    Enables ionotropic olfactory receptor activity. Involved in response to pheromone. Predicted to be located in dendrite membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adult antennal lobe; adult antennal lobe glomerulus; adult antennal sensillum; adult olfactory receptor neurons; and organism subdivision. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

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    See Or47b in Genome Data Viewer
    Location:
    47F1-47F1; 2-64 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11319710..11321312, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7207215..7208817, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene no mechanoreceptor potential A Neighboring gene shavenoid Neighboring gene lambdaTry

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Or47b plays a role in Drosophila males' preference for younger mates. Zhuang L, et al. Open Biol, 2016 Jun. PMID 27278650, Free PMC Article
    2. Hormonal Modulation of Pheromone Detection Enhances Male Courtship Success. Lin HH, et al. Neuron, 2016 Jun 15. PMID 27263969, Free PMC Article
    3. Or47b-neurons promote male-mating success in Drosophila. Lone SR, et al. Biol Lett, 2015 May. PMID 26018835, Free PMC Article
    4. Or47b receptor neurons mediate sociosexual interactions in the fruit fly Drosophila melanogaster. Lone SR, et al. J Biol Rhythms, 2012 Apr. PMID 22476771
    5. Decoding olfaction in Drosophila. Keller A, et al. Curr Opin Neurobiol, 2003 Feb. PMID 12593988

    See all (141) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results show that the olfactory receptor Or47b and Or47b-expressing neurons are required for males' preference for younger mates.
      Title: Or47b plays a role in Drosophila males' preference for younger mates.
    2. the sensitivity of Or47b neurons to a stimulatory pheromone, palmitoleic acid, is low in young males but high in older ones.
      Title: Hormonal Modulation of Pheromone Detection Enhances Male Courtship Success.
    3. Results indicate that Or47b receptor neurons are necessary for sociosexual interactions (SSIs), as ablation or silencing of these neurons has a severe impact on SSI.
      Title: Or47b receptor neurons mediate sociosexual interactions in the fruit fly Drosophila melanogaster.
    4. The or47b neuron major projected into glomerulu of VA1I, VA1m, VA1d and minor projected into DL3.
      Title: Olfactory neurons expressing identified receptor genes project to subsets of glomeruli within the antennal lobe of Drosophila melanogaster.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ionotropic olfactory receptor activity HDA PubMed 
    enables ionotropic olfactory receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables odorant binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus involved in sensory perception of smell HDA PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to pheromone IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sensory perception of smell NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in dendrite membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    odorant receptor 47b
    Names
    CG13206-PA
    Or47b-PA
    olfactory receptor 47E.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      11319710..11321312 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078966.3 → NP_523690.3  odorant receptor 47b [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523690.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P81922, Q9V5X4
      Related
      FBpp0087262, FBtr0088166
      Conserved Domains (1) summary
      pfam02949
      Location:88 → 402
      7tm_6; 7tm Odorant receptor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P81922.2 P81922

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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