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    Uqcc1 Ubiquinol-cytochrome c reductase complex assembly factor 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38758, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Uqcc1provided by FlyBase
    Official Full Name
    Ubiquinol-cytochrome c reductase complex assembly factor 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0035722
    Locus tag
    Dmel_CG10075
    See related
    AllianceGenome:FB:FBgn0035722
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10075; Dmel\CG10075; dUQCC1; UQCC1
    Summary
    Predicted to be involved in mitochondrial respiratory chain complex III assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in several structures, including adult head; anterior endoderm; embryonic/larval midgut primordium; gut section; and mesoderm. Orthologous to human UQCC1 (ubiquinol-cytochrome c reductase complex assembly factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Uqcc1 in Genome Data Viewer
    Location:
    65D4-65D4; 3-18 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6956946..6958108, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6950046..6951208, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene target of wingless Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Surfeit 1 Neighboring gene sugarless Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in Drosophila. Bosch JA, et al. Elife, 2022 Nov 8. PMID 36346220, Free PMC Article
    2. An efficient approach to isolate STAT regulated enhancers uncovers STAT92E fundamental role in Drosophila tracheal development. Sotillos S, et al. Dev Biol, 2010 Apr 15. PMID 20171201, Free PMC Article
    3. Identification of ER proteins involved in the functional organisation of the early secretory pathway in Drosophila cells by a targeted RNAi screen. Kondylis V, et al. PLoS One, 2011 Feb 23. PMID 21383842, Free PMC Article
    4. Close head-to-head juxtaposition of genes favors their coordinate regulation in Drosophila melanogaster. Herr DR, et al. FEBS Lett, 2004 Aug 13. PMID 15304339
    5. Many P-element insertions affect wing shape in Drosophila melanogaster. Weber K, et al. Genetics, 2005 Mar. PMID 15545659, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in mitochondrial respiratory chain complex III assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial respiratory chain complex III assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Ubiquinol-cytochrome c reductase complex assembly factor 1
    Names
    CG10075-PA
    Uqcc1-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6956946..6958108 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139807.4 → NP_648064.1  Ubiquinol-cytochrome c reductase complex assembly factor 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648064.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VRZ7
      Related
      FBpp0076648
      Conserved Domains (1) summary
      pfam03981
      Location:106 → 245
      Ubiq_cyt_C_chap; Ubiquinol-cytochrome C chaperone
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VRZ7 Q9VRZ7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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