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    CG10321 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37464, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10321provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034643
    Locus tag
    Dmel_CG10321
    See related
    AllianceGenome:FB:FBgn0034643
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10321
    Summary
    Enables DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10321 in Genome Data Viewer
    Location:
    57F5-57F5; 2-96 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21634679..21638399)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17522184..17525904)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene mahjong Neighboring gene antisense RNA:CR42547 Neighboring gene uncharacterized protein Neighboring gene Inositol hexakisphosphate kinase Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR43786

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Intrinsic protein disorder is insufficient to drive subnuclear clustering in embryonic transcription factors. Hannon CE, et al. Elife, 2024 Jan 26. PMID 38275292, Free PMC Article
    2. Identification of genes involved in the same pathways using a Hidden Markov Model-based approach. Senf A, et al. Bioinformatics, 2009 Nov 15. PMID 19720676
    3. Global analysis of target genes of 21 members of the ZAD transcription factor family in Drosophila melanogaster. Krystel J, et al. Gene, 2013 Jan 10. PMID 23085320, Free PMC Article
    4. Structural basis of diversity and homodimerization specificity of zinc-finger-associated domains in Drosophila. Bonchuk A, et al. Nucleic Acids Res, 2021 Feb 26. PMID 33638995, Free PMC Article
    5. A gain-of-function screen to identify genes that reduce lifespan in the adult of Drosophila melanogaster. Nakayama M, et al. BMC Genet, 2014 Apr 16. PMID 24739137, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription cis-regulatory region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10321-PA
    CG10321-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      21634679..21638399
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137750.3 → NP_611594.1  uncharacterized protein Dmel_CG10321, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611594.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2XY74, Q9W2F0
      Related
      FBpp0071577
      Conserved Domains (3) summary
      smart00868
      Location:12 → 80
      zf-AD; Zinc-finger associated domain (zf-AD)
      sd00017
      Location:627 → 647
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl22451
      Location:405 → 516
      ASF1_hist_chap; ASF1 like histone chaperone

    2. NM_001274195.2 → NP_001261124.1  uncharacterized protein Dmel_CG10321, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261124.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KFE8, Q2XY74
      Conserved Domains (3) summary
      smart00868
      Location:12 → 80
      zf-AD; Zinc-finger associated domain (zf-AD)
      sd00017
      Location:627 → 647
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl22451
      Location:405 → 516
      ASF1_hist_chap; ASF1 like histone chaperone
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KFE8 A0A0B4KFE8
    Q2XY74 Q2XY74
    Q9W2F0 Q9W2F0

    Gene LinkOut

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