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    Sdic3 Sperm-specific dynein intermediate chain 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318231, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sdic3provided by FlyBase
    Official Full Name
    Sperm-specific dynein intermediate chain 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0052823
    Locus tag
    Dmel_CG32823
    See related
    AllianceGenome:FB:FBgn0052823
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG32823; Dmel\CG32823; Sdic; Sdic:CG32823
    Summary
    Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Predicted to be involved in transport along microtubule. Predicted to be part of cytoplasmic dynein complex. Orthologous to human DYNC1I1 (dynein cytoplasmic 1 intermediate chain 1) and DYNC1I2 (dynein cytoplasmic 1 intermediate chain 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Sdic3 in Genome Data Viewer
    Location:
    19C1-19C1; 1-64 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20189440..20194227, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20083489..20088218, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Sperm-specific dynein intermediate chain 2 Neighboring gene pseudo Neighboring gene pseudo Neighboring gene Sperm-specific dynein intermediate chain A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A species-specific multigene family mediates differential sperm displacement in Drosophila melanogaster. Jayaswal V, et al. Evolution, 2018 Feb. PMID 29315521
    2. Functional evidence that a recently evolved Drosophila sperm-specific gene boosts sperm competition. Yeh SD, et al. Proc Natl Acad Sci U S A, 2012 Feb 7. PMID 22308475, Free PMC Article
    3. Paralog transcriptional differentiation in the D. melanogaster-specific gene family Sdic across populations and spermatogenesis stages. Clifton BD, et al. Commun Biol, 2023 Oct 20. PMID 37864070, Free PMC Article
    4. The use of a non-LTR element to date the formation of the Sdic gene cluster. Ponce R. Genetica, 2007 Nov. PMID 17351817
    5. The recent origin of the Sdic gene cluster in the melanogaster subgroup. Ponce R. Genetica, 2009 Apr. PMID 18587654

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables dynein heavy chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables dynein light chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transport along microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of cytoplasmic dynein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytoplasmic dynein complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Sperm-specific dynein intermediate chain 3
    Names
    CG32823-PE
    CG32823-PF
    CG32823-PG
    Sdic3-PE
    Sdic3-PF
    Sdic3-PG
    Sdic:CG32823

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      20189440..20194227 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167693.4 → NP_728323.3  Sperm-specific dynein intermediate chain 3, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728323.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      D5SHQ4, Q5BHW5, Q8IRZ3
      Conserved Domains (5) summary
      COG2319
      Location:224 → 523
      WD40; WD40 repeat [General function prediction only]
      COG2811
      Location:108 → 178
      NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
      pfam11540
      Location:23 → 51
      Dynein_IC2; Cytoplasmic dynein 1 intermediate chain 2
      sd00039
      Location:196 → 245
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:196 → 512
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_001298553.2 → NP_001285482.2  Sperm-specific dynein intermediate chain 3, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285482.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      D5SHQ4, Q5BHW5, Q8IRZ3
      Conserved Domains (5) summary
      COG2319
      Location:224 → 523
      WD40; WD40 repeat [General function prediction only]
      COG2811
      Location:108 → 178
      NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
      pfam11540
      Location:23 → 51
      Dynein_IC2; Cytoplasmic dynein 1 intermediate chain 2
      sd00039
      Location:196 → 245
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:196 → 512
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. NM_001298554.2 → NP_001285483.2  Sperm-specific dynein intermediate chain 3, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285483.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      D5SHQ4, Q5BHW5, Q8IRZ3
      Conserved Domains (5) summary
      COG2319
      Location:224 → 523
      WD40; WD40 repeat [General function prediction only]
      COG2811
      Location:108 → 178
      NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
      pfam11540
      Location:23 → 51
      Dynein_IC2; Cytoplasmic dynein 1 intermediate chain 2
      sd00039
      Location:196 → 245
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:196 → 512
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IRZ3 Q8IRZ3

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