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    CG6937 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42662, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6937provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038989
    Locus tag
    Dmel_CG6937
    See related
    AllianceGenome:FB:FBgn0038989
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg6937; Dmel\CG6937; NIFK
    Summary
    Predicted to enable mRNA binding activity. Predicted to be active in nucleolus. Is expressed in several structures, including embryonic/larval midgut primordium; gut section; larval muscle cell; mesoderm; and visceral mesoderm derivative. Orthologous to human NIFK (nucleolar protein interacting with the FHA domain of MKI67). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6937 in Genome Data Viewer
    Location:
    94B5-94B5; 3-75 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (22584773..22586209)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (18410495..18411931)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene COP9 signalosome subunit 6 Neighboring gene uncharacterized protein Neighboring gene Diphthamide methyltransferase Neighboring gene buttonless Neighboring gene Exchange factor for Arf 6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Conserved RNA Exonuclease Rexo5 Is Required for 3' End Maturation of 28S rRNA, 5S rRNA, and snoRNAs. Gerstberger S, et al. Cell Rep, 2017 Oct 17. PMID 29045842, Free PMC Article
    2. A Drosophila in vivo screen identifies store-operated calcium entry as a key regulator of adiposity. Baumbach J, et al. Cell Metab, 2014 Feb 4. PMID 24506874
    3. A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nybakken K, et al. Nat Genet, 2005 Dec. PMID 16311596, Free PMC Article
    4. The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins. Edlich-Muth C, et al. J Mol Biol, 2015 May 22. PMID 25813344, Free PMC Article
    5. Post-mating gene expression profiles of female Drosophila melanogaster in response to time and to four male accessory gland proteins. McGraw LA, et al. Genetics, 2008 Jul. PMID 18562649, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6937-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      22584773..22586209
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142809.4 → NP_651066.2  uncharacterized protein Dmel_CG6937 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651066.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7FNI7, Q9VCY1
      Related
      FBpp0083659
      Conserved Domains (3) summary
      COG0724
      Location:32 → 170
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12307
      Location:52 → 125
      RRM_NIFK_like; RNA recognition motif in nucleolar protein interacting with the FHA domain of pKI-67 (NIFK) and similar proteins
      pfam04050
      Location:253 → 304
      Upf2; Up-frameshift suppressor 2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SYV4 Q8SYV4
    Q9VCY1 Q9VCY1

    Gene LinkOut

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