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    Cdc27 Cell division cycle 27 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38798, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cdc27provided by FlyBase
    Official Full Name
    Cell division cycle 27provided by FlyBase
    Primary source
    FLYBASE:FBgn0012058
    Locus tag
    Dmel_CG8610
    See related
    AllianceGenome:FB:FBgn0012058
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Apc3; APC3; cdc27; CDC27; CDC27Dm; CG8610; Dmcdc27; Dmel\CG8610; l(3)L7123; mks
    Summary
    Involved in anaphase-promoting complex-dependent catabolic process. Located in nucleus. Part of anaphase-promoting complex. Colocalizes with condensed chromosome. Is expressed in organism. Orthologous to human CDC27 (cell division cycle 27). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See Cdc27 in Genome Data Viewer
    Location:
    65E9-65E9; 3-19 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7245481..7249340, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7238581..7242440, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Neosin Neighboring gene mitochondrial ribosomal protein L50 Neighboring gene meiotic P22 Neighboring gene antisense RNA:CR43470 Neighboring gene Mediator complex subunit 4 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    cell division cycle 27
    Names
    CG8610-PA
    CG8610-PB
    Cdc27-PA
    Cdc27-PB
    cell division cycle 27 ortholog
    makos

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      7245481..7249340 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274574.1NP_001261503.1  cell division cycle 27, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261503.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VS37
      Conserved Domains (6) summary
      COG0457
      Location:590850
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:678708
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:713746
      TPR_1; Tetratricopeptide repeat
      pfam12895
      Location:1694
      ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3
      pfam13414
      Location:67145
      TPR_11; TPR repeat
      pfam13424
      Location:539601
      TPR_12; Tetratricopeptide repeat
    2. NM_139836.3NP_648093.2  cell division cycle 27, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648093.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VS37
      Related
      FBpp0076600
      Conserved Domains (6) summary
      COG0457
      Location:590850
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:678708
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:713746
      TPR_1; Tetratricopeptide repeat
      pfam12895
      Location:1694
      ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3
      pfam13414
      Location:67145
      TPR_11; TPR repeat
      pfam13424
      Location:539601
      TPR_12; Tetratricopeptide repeat