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    CG44774 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31424, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG44774provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0266000
    Locus tag
    Dmel_CG44774
    See related
    AllianceGenome:FB:FBgn0266000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4068; CR43698; CR43699; Dmel\CG44774; hp-CG4068
    Old locus tag
    Dmel_CG4068; Dmel_CR43698; Dmel_CR43699
    Summary
    Predicted to be involved in negative regulation of cell migration. Predicted to be part of Sin3-type complex. Is expressed in several structures, including auditory system neurons; embryonic/larval midgut primordium; ganglia; gut section; and mesoderm. Orthologous to human SINHCAF (SIN3-HDAC complex associated factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG44774 in Genome Data Viewer
    Location:
    4D6-4D7; 1-9 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (4926664..4938105, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (4815711..4832138, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene hairpin RNA:CR46342 Neighboring gene uncharacterized protein Neighboring gene Heparan-alpha-glucosaminide N-acetyltransferase Neighboring gene long non-coding RNA:CR44833 Neighboring gene Protein tyrosine phosphatase 4E Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Organization of projection neurons and local neurons of the primary auditory center in the fruit fly Drosophila melanogaster. Matsuo E, et al. J Comp Neurol, 2016 Apr 15. PMID 26762251
    2. Loqs and R2D2 act sequentially in the siRNA pathway in Drosophila. Marques JT, et al. Nat Struct Mol Biol, 2010 Jan. PMID 20037596, Free PMC Article
    3. Redundancy and compensation in axon guidance: genetic analysis of the Drosophila Ptp10D/Ptp4E receptor tyrosine phosphatase subfamily. Jeon M, et al. Neural Dev, 2008 Jan 31. PMID 18237413, Free PMC Article
    4. Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences. Hartig JV, et al. EMBO J, 2009 Oct 7. PMID 19644447, Free PMC Article
    5. Opposite effects of Drosophila C3PO on gene silencing mediated by esi-2.1 and miRNA-bantam. Liu Y, et al. Acta Biochim Biophys Sin (Shanghai), 2019 Feb 1. PMID 30576408

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of cell migration ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of Sin3-type complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Sin3-type complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG44774-PA
    CG44774-PB
    CG44774-PC
    CG44774-PD
    CG44774-PE
    CG44774-PF
    CG44774-PG
    CG44774-PI

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      4926664..4938105 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001103410.3 → NP_001096880.1  uncharacterized protein Dmel_CG44774, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096880.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JUX7, Q8T0A8
      Conserved Domains (1) summary
      pfam15396
      Location:2 → 269
      FAM60A; Protein Family FAM60A

    2. NM_206627.3 → NP_996350.1  uncharacterized protein Dmel_CG44774, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996350.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0A8, Q9W4F6
      Conserved Domains (1) summary
      pfam15396
      Location:2 → 269
      FAM60A; Protein Family FAM60A

    3. NM_001272319.1 → NP_001259248.1  uncharacterized protein Dmel_CG44774, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259248.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0A8, Q9W4F6
      Conserved Domains (1) summary
      pfam15396
      Location:2 → 269
      FAM60A; Protein Family FAM60A

    4. NM_001103411.3 → NP_001096881.1  uncharacterized protein Dmel_CG44774, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096881.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JUX7, Q8T0A8
      Conserved Domains (1) summary
      pfam15396
      Location:2 → 269
      FAM60A; Protein Family FAM60A

    5. NM_001103412.2 → NP_001096882.1  uncharacterized protein Dmel_CG44774, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096882.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JUX7, Q8T0A8
      Conserved Domains (1) summary
      pfam15396
      Location:2 → 269
      FAM60A; Protein Family FAM60A

    6. NM_131971.4 → NP_572199.2  uncharacterized protein Dmel_CG44774, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572199.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0A8, Q9W4F6
      Related
      FBpp0309834
      Conserved Domains (1) summary
      pfam15396
      Location:2 → 269
      FAM60A; Protein Family FAM60A

    7. NM_001272318.2 → NP_001259247.1  uncharacterized protein Dmel_CG44774, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259247.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0A8, Q9W4F6
      Conserved Domains (1) summary
      pfam15396
      Location:2 → 269
      FAM60A; Protein Family FAM60A

    8. NM_001297945.1 → NP_001284874.1  uncharacterized protein Dmel_CG44774, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284874.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0A8, Q9W4F6
      Conserved Domains (1) summary
      pfam15396
      Location:2 → 269
      FAM60A; Protein Family FAM60A
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8JUX7 A8JUX7
    Q8T0A8 Q8T0A8
    Q9W4F6 Q9W4F6

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