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    CG2493 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35316, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2493provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032864
    Locus tag
    Dmel_CG2493
    See related
    AllianceGenome:FB:FBgn0032864
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    38C.55; Dmel\CG2493; Prcp
    Summary
    Enables serine hydrolase activity. Predicted to be involved in proteolysis. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; foregut primordium; hindgut proper primordium; and mesoderm. Orthologous to human PRCP (prolylcarboxypeptidase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2493 in Genome Data Viewer
    Location:
    38C8-38C8; 2-54 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20461585..20463444, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20461585..20463444, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44980 Neighboring gene Cell division cycle 23 Neighboring gene long non-coding RNA:CR43234 Neighboring gene long non-coding RNA:CR46416 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Patterns of mutation and selection at synonymous sites in Drosophila. Singh ND, et al. Mol Biol Evol, 2007 Dec. PMID 18000010
    2. Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth. Sokol NS, et al. Genes Dev, 2005 Oct 1. PMID 16166373, Free PMC Article
    3. Identification of germ plasm-enriched mRNAs in Drosophila melanogaster by the cDNA microarray technique. Szuperák M, et al. Gene Expr Patterns, 2005 Jun. PMID 15939385
    4. Functional Analysis of the Glucuronyltransferases GlcAT-P and GlcAT-S of Drosophila melanogaster: Distinct Activities towards the O-linked T-antigen. Breloy I, et al. Biomolecules, 2016 Jan 6. PMID 26751495, Free PMC Article
    5. Mammalian and Invertebrate Models as Complementary Tools for Gaining Mechanistic Insight on Muscle Responses to Spaceflight. Cahill T, et al. Int J Mol Sci, 2021 Aug 31. PMID 34502375, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables dipeptidyl-peptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine hydrolase activity HDA PubMed 
    enables serine-type exopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2493-PA
    CG2493-PB
    peptidase S28
    NP_001260630.1
    NP_610037.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      20461585..20463444 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136193.2 → NP_610037.1  uncharacterized protein Dmel_CG2493, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610037.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIM0
      Related
      FBpp0080895
      Conserved Domains (1) summary
      cl21494
      Location:43 → 464
      Abhydrolase; alpha/beta hydrolases

    2. NM_001273701.1 → NP_001260630.1  uncharacterized protein Dmel_CG2493, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260630.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIM0
      Conserved Domains (1) summary
      cl21494
      Location:43 → 464
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VIM0 Q9VIM0

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