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    CG32576 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318095, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32576provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052576
    Locus tag
    Dmel_CG32576
    See related
    AllianceGenome:FB:FBgn0052576
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-AE003501.1; BcDNA:RE29988; Dmel\CG32576; NEST:bs01h05
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and retrograde transport, endosome to Golgi. Predicted to be active in endoplasmic reticulum and membrane. Orthologous to several human genes including GOLT1B (golgi transport 1B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32576 in Genome Data Viewer
    Location:
    14B7-14B8; 1-53 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16285953..16288533, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (16179986..16182566, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Proteasome alpha4 subunit Neighboring gene easily shocked Neighboring gene Ubiquinol-cytochrome c reductase 14 kDa subunit Neighboring gene cabeza Neighboring gene Endoplasmic reticulum protein 44 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SMN complex member Gemin3 self-interacts and has a functional relationship with ALS-linked proteins TDP-43, FUS and Sod1. Cacciottolo R, et al. Sci Rep, 2019 Dec 10. PMID 31822699, Free PMC Article
    2. Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS. Xia R, et al. Mol Neurodegener, 2012 Mar 24. PMID 22443542, Free PMC Article
    3. The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span. Wang JW, et al. J Clin Invest, 2011 Oct. PMID 21881207, Free PMC Article
    4. Endogenously imprinted genes in Drosophila melanogaster. McEachern LA, et al. Mol Genet Genomics, 2014 Aug. PMID 24658702
    5. X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila. Legube G, et al. Genes Dev, 2006 Apr 1. PMID 16547175, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in retrograde transport, endosome to Golgi IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32576-PA
    CG32576-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      16285953..16288533 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001014746.3 → NP_001014746.1  uncharacterized protein Dmel_CG32576, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001014746.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q59E43, Q8SYX1
      Conserved Domains (1) summary
      cl02130
      Location:4 → 116
      Got1; Got1/Sft2-like family

    2. NM_167492.4 → NP_727945.1  uncharacterized protein Dmel_CG32576, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727945.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IR19, Q8SYX1
      Related
      FBpp0074024
      Conserved Domains (1) summary
      cl02130
      Location:4 → 116
      Got1; Got1/Sft2-like family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q59E43 Q59E43
    Q8IR19 Q8IR19
    Q8SYX1 Q8SYX1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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