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    MAPKKK14 mitogen-activated protein kinase kinase kinase 14 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817555, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MAPKKK14
    Official Full Name
    mitogen-activated protein kinase kinase kinase 14
    Primary source
    TAIR:AT2G30040
    Locus tag
    AT2G30040
    See related
    Araport:AT2G30040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F23F1.4; F23F1_4; mitogen-activated protein kinase kinase kinase 14
    Summary
    member of MEKK subfamily
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    Genomic context

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    See MAPKKK14 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (12821569..12823169)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Protein phosphatase 2C family protein Neighboring gene ncRNA Neighboring gene transducin family protein / WD-40 repeat family protein Neighboring gene Pleckstrin homology (PH) domain superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Wounding and Insect Feeding Trigger Two Independent MAPK Pathways with Distinct Regulation and Kinetics. Sözen C, et al. Plant Cell, 2020 Jun. PMID 32265268, Free PMC Article
    2. Plastids are major regulators of light signaling in Arabidopsis. Ruckle ME, et al. Plant Physiol, 2012 May. PMID 22383539, Free PMC Article
    3. Members of the Plant CRK Superfamily Are Capable of Trans- and Autophosphorylation of Tyrosine Residues. Nemoto K, et al. J Biol Chem, 2015 Jul 3. PMID 25969537, Free PMC Article
    4. Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system. Nemoto K, et al. Phytochemistry, 2011 Jul. PMID 21477822
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NM_128559.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity HDA PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein autophosphorylation HDA PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase 14
    NP_180565.1
    • mitogen-activated protein kinase kinase kinase 14 (MAPKKK14); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: mitogen-activated protein kinase kinase kinase 13 (TAIR:AT1G07150.2); Has 109483 Blast hits to 108488 proteins in 3028 species: Archae - 134; Bacteria - 12042; Metazoa - 41245; Fungi - 11323; Plants - 26137; Viruses - 476; Other Eukaryotes - 18126 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12821569..12823169
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128559.3 → NP_180565.1  mitogen-activated protein kinase kinase kinase 14 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180565.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VSA5, O64741
      Conserved Domains (2) summary
      smart00220
      Location:17 → 270
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06606
      Location:17 → 270
      STKc_MAPKKK; Catalytic domain of the Serine/Threonine Kinase, Mitogen-Activated Protein Kinase Kinase Kinase
    Nucleotide Protein
    Heading Accession and Version

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