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    PRK2A Leucine-rich repeat protein kinase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 815274, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PRK2A
    Official Full Name
    Leucine-rich repeat protein kinase family protein
    Primary source
    TAIR:AT2G07040
    Locus tag
    AT2G07040
    See related
    Araport:AT2G07040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtPRK2; ATPRK2A; pollen receptor like kinase 2; PRK2; T4E14.15; T4E14_15
    Summary
    Pollen receptor kinase. Coexpression of AtPRK2a with AtRopGEF12 resulted in isotropic pollen tube growth.
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    Genomic context

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    See PRK2A in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (2916416..2919392)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene kinase with adenine nucleotide alpha hydrolases-like domain-containing protein Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene cycloartenol synthase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The juxtamembrane and carboxy-terminal domains of Arabidopsis PRK2 are critical for ROP-induced growth in pollen tubes. Zhao XY, et al. J Exp Bot, 2013 Dec. PMID 24136420, Free PMC Article
    2. A distinct mechanism regulating a pollen-specific guanine nucleotide exchange factor for the small GTPase Rop in Arabidopsis thaliana. Zhang Y, et al. Proc Natl Acad Sci U S A, 2007 Nov 20. PMID 18000057, Free PMC Article
    3. AtPRK2 promotes ROP1 activation via RopGEFs in the control of polarized pollen tube growth. Chang F, et al. Mol Plant, 2013 Jul. PMID 23024212, Free PMC Article
    4. A membrane protein/signaling protein interaction network for Arabidopsis version AMPv2. Lalonde S, et al. Front Physiol, 2010. PMID 21423366, Free PMC Article
    5. An extracellular network of Arabidopsis leucine-rich repeat receptor kinases. Smakowska-Luzan E, et al. Nature, 2018 Jan 18. PMID 29320478, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtPRK2-induced tube depolarization depends on its interaction with RopGEF12.The juxtamembrane and carboxy-terminal domains of Arabidopsis PRK2 are critical for ROP-induced growth in pollen tubes.
      Title: The juxtamembrane and carboxy-terminal domains of Arabidopsis PRK2 are critical for ROP-induced growth in pollen tubes.
    2. AtPRK2 acts as a positive regulator of the ROP1 signaling pathway most likely by activating RopGEF1 through phosphorylation
      Title: AtPRK2 promotes ROP1 activation via RopGEFs in the control of polarized pollen tube growth.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_126680.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen tube growth IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of pollen tube growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in pollen tube IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Leucine-rich repeat protein kinase family protein
    NP_178721.3
    • PRK2A; FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation, transmembrane receptor protein tyrosine kinase signaling pathway, pollen tube growth; LOCATED IN: plasma membrane; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: Leucine-rich repeat protein kinase family protein (TAIR:AT5G35390.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      2916416..2919392
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126680.4 → NP_178721.3  Leucine-rich repeat protein kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178721.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84JQ4, Q9ZVV7
      UniProtKB/TrEMBL
      A0A178VQY1
      Conserved Domains (5) summary
      sd00033
      Location:90 → 112
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00069
      Location:342 → 607
      Pkinase; Protein kinase domain
      pfam08263
      Location:23 → 61
      LRRNT_2; Leucine rich repeat N-terminal domain
      pfam13855
      Location:113 → 172
      LRR_8; Leucine rich repeat
      cl21453
      Location:344 → 612
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84JQ4.1

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