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    integral membrane metal-binding family protein (DUF2296) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816969, updated on 18-Sep-2024

    Summary

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    Official Full Name
    integral membrane metal-binding family protein (DUF2296)
    Primary source
    TAIR:AT2G24330
    Locus tag
    AT2G24330
    See related
    Araport:AT2G24330
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T28I24.6; T28I24_6
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    5
    Sequence:
    Chromosome: 2; NC_003071.7 (10347018..10349921, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Calmodulin-binding protein Neighboring gene ncRNA Neighboring gene TPRXL Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Endoplasmic Reticulum (ER) Membrane Proteins (LUNAPARKs) are Required for Proper Configuration of the Cortical ER Network in Plant Cells. Ueda H, et al. Plant Cell Physiol, 2018 Oct 1. PMID 30010972
    2. Arabidopsis Lunapark proteins are involved in ER cisternae formation. Kriechbaumer V, et al. New Phytol, 2018 Aug. PMID 29797722, Free PMC Article
    3. LUNAPARK Is an E3 Ligase That Mediates Degradation of ROOT HAIR DEFECTIVE3 to Maintain a Tubular ER Network in Arabidopsis. Sun J, et al. Plant Cell, 2020 Sep. PMID 32616662, Free PMC Article
    4. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LUNAPARK Is an E3 Ligase That Mediates Degradation of ROOT HAIR DEFECTIVE3 to Maintain a Tubular ER Network in Arabidopsis.
      Title: LUNAPARK Is an E3 Ligase That Mediates Degradation of ROOT HAIR DEFECTIVE3 to Maintain a Tubular ER Network in Arabidopsis.
    2. AtLNP1 and AtLNP2 are involved in determining the network morphology of the plant endoplasmic reticulum (ER), possibly by regulating the formation of ER cisternae.[AtLNP1]
      Title: Arabidopsis Lunapark proteins are involved in ER cisternae formation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_127995.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within endoplasmic reticulum cisternal network assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in endoplasmic reticulum tubular network organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    integral membrane metal-binding family protein (DUF2296)
    NP_180010.1
    • Protein of unknown function (DUF2296); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF2296 (InterPro:IPR019273); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF2296) (TAIR:AT4G31080.1); Has 315 Blast hits to 309 proteins in 114 species: Archae - 0; Bacteria - 0; Metazoa - 149; Fungi - 81; Plants - 79; Viruses - 0; Other Eukaryotes - 6 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      10347018..10349921 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127995.3 → NP_180010.1  integral membrane metal-binding family protein (DUF2296) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180010.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZQ34
      UniProtKB/TrEMBL
      A0A178VV17, A0A5S9X0Z3, Q541V7
      Conserved Domains (1) summary
      pfam10058
      Location:292 → 342
      zinc_ribbon_10; Predicted integral membrane zinc-ribbon metal-binding protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZQ34.1

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