ELF8 binding protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: ELF8
Official Full Name: binding protein
Primary source: TAIR:AT2G06210
Locus tag: AT2G06210
See related: Araport:AT2G06210
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: EARLY FLOWERING 8; F5K7.3; F5K7_3; VERNALIZATION INDEPENDENCE 6; VIP6
Summary: Encodes a yeast CTR9 homolog that is involved in the control of flowering time by elevating FLC expression to a level that creates the vernalization-responsive, winter-annual habit. Yeast CTR9 is a component of a five-member PAF1 complex that associates with RNA pol II and is thought to regulate gene expression by recruiting SET1 (a histone 3 Lys 4 [H3-K4] methyl transferase) to the initially transcribed [5'] regions of target chromatin. Mutants display reduced H3-K4 methylation in both FLC and FLM chromatin.
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Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_126631.7

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of flower development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of DNA-templated transcription	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of Cdc73/Paf1 complex	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

NP_178674.7

EARLY FLOWERING 8 (ELF8); FUNCTIONS IN: binding; INVOLVED IN: positive regulation of transcription, DNA-dependent, histone methylation, negative regulation of flower development; LOCATED IN: membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide TPR2 (InterPro:IPR013105), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT3G04240.1); Has 39956 Blast hits to 25035 proteins in 1980 species: Archae - 1189; Bacteria - 13149; Metazoa - 9789; Fungi - 2497; Plants - 1315; Viruses - 192; Other Eukaryotes - 11825 (source: NCBI BLink).