sphere organelles protein-like protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: sphere organelles protein-like protein
Primary source: TAIR:AT1G13030
Locus tag: AT1G13030
See related: Araport:AT1G13030
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: Atcoilin; coilin; COILIN; F3F19.5; F3F19_5
Summary: Encodes a plant coilin, a protein that in other organisms is a major structural scaffolding protein necessary for Cajal body formation, composition and activity. It has been shown to bind both U1 and U1 snRNAs in vitro.
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 13

Sequence:: Chromosome: 1; NC_003070.9 (4444043..4447412, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A GFP splicing reporter in a coilin mutant background reveals links between alternative splicing, siRNAs, and coilin function in Arabidopsis thaliana.
Title: A GFP splicing reporter in a coilin mutant background reveals links between alternative splicing, siRNAs, and coilin function in Arabidopsis thaliana.
The transcriptional and splicing changes observed in coilin mutants are not accompanied by gross phenotypic abnormalities or dramatically altered stress responses, supporting a role for coilin in fine tuning gene expression
Title: Identification of Coilin Mutants in a Screen for Enhanced Expression of an Alternatively Spliced GFP Reporter Gene in Arabidopsis thaliana.
Physical properties of deletion mutants indicate that coilin might consist of an N-terminal globular domain, a central highly disordered domain and a C-terminal domain containing a Tudor-like structure adjacent to a disordered C terminus. [coilin]
Title: Plant coilin: structural characteristics and RNA-binding properties.
interaction between viral protein and coilin
Title: Movement protein of hordeivirus interacts in vitro and in vivo with coilin, a major structural protein of Cajal bodies.
Atcoilin is required for Cajal body formation in Arabidopsis. [atcoilin]
Title: A distant coilin homologue is required for the formation of cajal bodies in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_101173.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables U1 snRNA binding	IDA Inferred from Direct Assay more info	PubMed
enables U2 snRNA binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA processing	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: sphere organelles protein-like protein

NP_172762.2

sphere organelles protein-related; Has 14464 Blast hits to 9695 proteins in 837 species: Archae - 14; Bacteria - 1320; Metazoa - 4989; Fungi - 1376; Plants - 652; Viruses - 103; Other Eukaryotes - 6010 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

4444043..4447412 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_101173.5 → NP_172762.2 sphere organelles protein-like protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_172762.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8RWK8, Q9SAD8

UniProtKB/TrEMBL

A0A178W997, A0A5S9U6V6

Conserved Domains (1) summary

pfam15862
Location:6 → 131

Coilin_N; Coilin N-terminus