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    NEK2 NIMA-related kinase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819641, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NEK2
    Official Full Name
    NIMA-related kinase 2
    Primary source
    TAIR:AT3G04810
    Locus tag
    AT3G04810
    See related
    Araport:AT3G04810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATNEK2; NIMA-related kinase 2; NIMA-RELATED KINASE2; T9J14.24; T9J14_24
    Summary
    Encodes AtNek2, a member of the NIMA-related serine/threonine kinases (Neks) that have been linked to cell-cycle regulation in fungi and mammals. Plant Neks might be involved in plant development processes.
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    Genomic context

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    See NEK2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    16
    Sequence:
    Chromosome: 3; NC_003074.8 (1317245..1321294)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Ribose 5-phosphate isomerase, type A protein Neighboring gene ncRNA Neighboring gene translocase inner membrane subunit 23-3 Neighboring gene ncRNA Neighboring gene Pseudouridine synthase family protein Neighboring gene Protein prenylyltransferase superfamily protein Neighboring gene Ribosomal protein S3Ae

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001337542.1
    NM_111353.4
    NM_202492.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    NIMA-related kinase 2
    NP_187132.1
    • NIMA-related kinase 2 (NEK2); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NIMA-related kinase 3 (TAIR:AT5G28290.1); Has 124232 Blast hits to 122078 proteins in 4151 species: Archae - 113; Bacteria - 14232; Metazoa - 45825; Fungi - 12238; Plants - 30614; Viruses - 487; Other Eukaryotes - 20723 (source: NCBI BLink).
    NP_974221.2
    • NIMA-related kinase 2 (NEK2); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NIMA-related kinase 3 (TAIR:AT5G28290.1); Has 124376 Blast hits to 122221 proteins in 4182 species: Archae - 113; Bacteria - 14280; Metazoa - 45892; Fungi - 12262; Plants - 30619; Viruses - 487; Other Eukaryotes - 20723 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1317245..1321294
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_202492.3 → NP_974221.2  NIMA-related kinase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974221.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94K93, Q9CAU7
      UniProtKB/TrEMBL
      A0A178V8L3, A0A5S9X955, A0A654F468, B9DH51, B9DHE1
      Conserved Domains (1) summary
      cd08215
      Location:3 → 258
      STKc_Nek; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase

    2. NM_111353.4 → NP_187132.1  NIMA-related kinase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187132.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94K93, Q9CAU7
      UniProtKB/TrEMBL
      A0A178V8L3, A0A5S9X955, A0A654F468, B9DH51, B9DHE1
      Conserved Domains (1) summary
      cd08215
      Location:3 → 258
      STKc_Nek; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase

    3. NM_001337542.1 → NP_001327439.1  NIMA-related kinase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94K93, Q9CAU7
      UniProtKB/TrEMBL
      A0A178V8L3, A0A5S9X955, A0A654F468, B9DH51, B9DHE1
      Conserved Domains (1) summary
      cd08215
      Location:3 → 258
      STKc_Nek; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CAU7.1

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