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    MBAC1 Mitochondrial substrate carrier family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817949, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MBAC1
    Official Full Name
    Mitochondrial substrate carrier family protein
    Primary source
    TAIR:AT2G33820
    Locus tag
    AT2G33820
    See related
    Araport:AT2G33820
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATMBAC1; BAC1; T1B8.12; T1B8_12
    Summary
    encodes a mitochondrial ornithine transporter which exports ornithine from the mitochondrion to the cytosol
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    Genomic context

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    See MBAC1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    8
    Sequence:
    Chromosome: 2; NC_003071.7 (14306293..14308367, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene squamosa promoter binding protein-like 3 Neighboring gene Dormancy/auxin associated family protein Neighboring gene Zinc finger C-x8-C-x5-C-x3-H type family protein Neighboring gene Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis mitochondria have two basic amino acid transporters with partially overlapping specificities and differential expression in seedling development. Palmieri L, et al. Biochim Biophys Acta, 2006 Sep-Oct. PMID 16730327
    2. Identification of a mitochondrial transporter for basic amino acids in Arabidopsis thaliana by functional reconstitution into liposomes and complementation in yeast. Hoyos ME, et al. Plant J, 2003 Mar. PMID 12631327
    3. A user-friendly platform for yeast two-hybrid library screening using next generation sequencing. Erffelinck ML, et al. PLoS One, 2018. PMID 30576311, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Both BAC1 and BAC2 displayed highest affinity for arginine with similar Km and Vmax. However, BAC2 transported citrulline for which BAC1 had little or no affinity. Furthermore, BAC2 was less stereospecific than BAC1.
      Title: Arabidopsis mitochondria have two basic amino acid transporters with partially overlapping specificities and differential expression in seedling development.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001336471.1
    NM_001336472.1
    NM_001336473.1
    NM_128941.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables L-histidine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-lysine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-ornithine transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Mitochondrial substrate carrier family protein
    NP_180938.2
    • MBAC1; FUNCTIONS IN: arginine transmembrane transporter activity, L-histidine transmembrane transporter activity, L-lysine transmembrane transporter activity, L-ornithine transmembrane transporter activity, binding; INVOLVED IN: transport, mitochondrial transport, transmembrane transport; LOCATED IN: mitochondrial inner membrane, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial substrate carrier (InterPro:IPR001993), Mitochondrial substrate/solute carrier (InterPro:IPR018108), Adenine nucleotide translocator 1 (InterPro:IPR002113); BEST Arabidopsis thaliana protein match is: Mitochondrial substrate carrier family protein (TAIR:AT5G46800.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14306293..14308367 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128941.3 → NP_180938.2  Mitochondrial substrate carrier family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180938.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P93016, Q84UC7
      UniProtKB/TrEMBL
      A0A178VWG0, A0A5S9X479
      Conserved Domains (1) summary
      pfam00153
      Location:13 → 104
      Mito_carr; Mitochondrial carrier protein

    2. NM_001336472.1 → NP_001324476.1  Mitochondrial substrate carrier family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B094, A0A5S9X479

    3. NM_001336471.1 → NP_001324477.1  Mitochondrial substrate carrier family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B093

    4. NM_001336473.1 → NP_001324478.1  Mitochondrial substrate carrier family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B0A2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84UC7.1

    Gene LinkOut

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