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    Nek7 NIMA-related kinase 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820397, updated on 18-Sep-2024

    Summary

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    Official Symbol
    Nek7
    Official Full Name
    NIMA-related kinase 7
    Primary source
    TAIR:AT3G12200
    Locus tag
    AT3G12200
    See related
    Araport:AT3G12200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtNek7; NIMA-related kinase 7
    Summary
    Encodes AtNek7, a member of the NIMA-related serine/threonine kinases (Neks) that have been linked to cell-cycle regulation in fungi and mammals. Plant Neks might be involved in plant development processes.
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    Genomic context

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    See Nek7 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    14
    Sequence:
    Chromosome: 3; NC_003074.8 (3886957..3891000, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene Cornichon family protein Neighboring gene golgin family A protein Neighboring gene serine carboxypeptidase-like 17 Neighboring gene DNA binding protein Neighboring gene serine carboxypeptidase-like 16

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays. Popescu SC, et al. Proc Natl Acad Sci U S A, 2007 Mar 13. PMID 17360592, Free PMC Article
    2. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001202938.1
    NM_001337978.1
    NM_001337979.1
    NM_112055.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    NIMA-related kinase 7
    NP_001189867.1
    • NIMA-related kinase 7 (Nek7); FUNCTIONS IN: protein serine/threonine kinase activity, protein tyrosine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Tyrosine-protein kinase, active site (InterPro:IPR008266), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: NIMA-related kinase 5 (TAIR:AT3G20860.1).
    NP_187827.1
    • NIMA-related kinase 7 (Nek7); FUNCTIONS IN: protein tyrosine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, active site (InterPro:IPR008266), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: NIMA-related kinase 5 (TAIR:AT3G20860.1); Has 97728 Blast hits to 96752 proteins in 2792 species: Archae - 79; Bacteria - 10263; Metazoa - 38148; Fungi - 10471; Plants - 20939; Viruses - 426; Other Eukaryotes - 17402 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3886957..3891000 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112055.5 → NP_187827.1  NIMA-related kinase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187827.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W4P0, Q9LHI7
      UniProtKB/TrEMBL
      A0A178V9U6, A0A5S9XBA9
      Conserved Domains (2) summary
      pfam00069
      Location:19 → 271
      Pkinase; Protein kinase domain
      cl21453
      Location:18 → 273
      PKc_like; Protein Kinases, catalytic domain

    2. NM_001337978.1 → NP_001327416.1  NIMA-related kinase 7 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V9U6, A0A1I9LS93, A0A5S9XBA9

    3. NM_001202938.1 → NP_001189867.1  NIMA-related kinase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189867.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654F6A7, F4J8P0
      Conserved Domains (2) summary
      pfam00069
      Location:19 → 281
      Pkinase; Protein kinase domain
      cl21453
      Location:18 → 283
      PKc_like; Protein Kinases, catalytic domain

    4. NM_001337979.1 → NP_001327417.1  NIMA-related kinase 7 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V9U6, A0A1I9LS94, A0A5S9XBA9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LHI7.1

    Gene LinkOut

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