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    pachytene checkpoint-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828573, updated on 18-Sep-2024

    Summary

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    Official Full Name
    pachytene checkpoint-like protein
    Primary source
    TAIR:AT4G24710
    Locus tag
    AT4G24710
    See related
    Araport:AT4G24710
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F22K18.90; F22K18_90
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    14
    Sequence:
    Chromosome: 4; NC_003075.7 (12745547..12749134, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene modifier of snc1 Neighboring gene ubiquitin-associated (UBA)/TS-N domain-containing protein / octicosapeptide/Phox/Bemp1 (PB1) domain-containing protein Neighboring gene uncharacterized protein Neighboring gene high-affinity nitrate transporter-like protein Neighboring gene manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. State changes of the HORMA protein ASY1 are mediated by an interplay between its closure motif and PCH2. Yang C, et al. Nucleic Acids Res, 2020 Nov 18. PMID 32558910, Free PMC Article
    2. Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers. Lambing C, et al. PLoS Genet, 2015 Jul. PMID 26182244, Free PMC Article
    3. COMET Functions as a PCH2 Cofactor in Regulating the HORMA Domain Protein ASY1. Balboni M, et al. Curr Biol, 2020 Nov 2. PMID 32857973
    4. Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase. Van Leene J, et al. Nat Plants, 2019 Mar. PMID 30833711
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. COMET Functions as a PCH2 Cofactor in Regulating the HORMA Domain Protein ASY1.
      Title: COMET Functions as a PCH2 Cofactor in Regulating the HORMA Domain Protein ASY1.
    2. State changes of the HORMA protein ASY1 are mediated by an interplay between its closure motif and PCH2.
      Title: State changes of the HORMA protein ASY1 are mediated by an interplay between its closure motif and PCH2.
    3. PCH2 is required for remodelling of the chromosome axis during synaptonemal complex formation. [PCH2]
      Title: Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001341695.1
    NM_001341697.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chiasma assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in homologous chromosome pairing at meiosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within synaptonemal complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in synaptonemal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pachytene checkpoint-like protein
    NP_001320058.1
    • P-loop containing nucleoside triphosphate hydrolases superfamily protein; FUNCTIONS IN: nucleoside-triphosphatase activity, ATPase activity, nucleotide binding, ATP binding; EXPRESSED IN: shoot apex, embryo, flower, seed; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, conserved site (InterPro:IPR003960), Chaperonin clpA/B (InterPro:IPR001270); BEST Arabidopsis thaliana protein match is: ATPase, AAA-type, CDC48 protein (TAIR:AT3G53230.1); Has 23595 Blast hits to 21814 proteins in 2884 species: Archae - 1432; Bacteria - 8057; Metazoa - 4130; Fungi - 3211; Plants - 2291; Viruses - 16; Other Eukaryotes - 4458 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      12745547..12749134 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118604.5 → NP_194202.4  pachytene checkpoint-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UX56, A0A1P8B3X3, A0A654FSG2
      Conserved Domains (1) summary
      cd19508
      Location:163 → 361
      RecA-like_Pch2-like; ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains

    2. NM_001341696.1 → NP_001328224.1  pachytene checkpoint-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B3Y3

    3. NM_001341695.1 → NP_001320058.1  pachytene checkpoint-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JR10, Q67ZT1, Q8H1F9, Q9SB66
      UniProtKB/TrEMBL
      A0A178UX56

    4. NM_001341697.1 → NP_001328225.1  pachytene checkpoint-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B3Y3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8H1F9.1

    Gene LinkOut

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