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    RPS6 ribosomal protein S6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829298, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RPS6
    Official Full Name
    ribosomal protein S6
    Primary source
    TAIR:AT4G31700
    Locus tag
    AT4G31700
    See related
    Araport:AT4G31700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtRPS6; F28M20.110; F28M20_110; ribosomal protein S6; RIBOSOMAL PROTEIN S6; RPS6A
    Summary
    Encodes a putative ribosomal protein S6 (rps6a). RPS6A and RPS6B are fully redundant and essential during gametogenesis.
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    Genomic context

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    See RPS6 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (15345979..15347804, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene transcriptional factor B3 family protein Neighboring gene tRNA-Met Neighboring gene glutamate receptor 2.4 Neighboring gene uncharacterized protein Neighboring gene TBP-associated factor II 15

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The two Arabidopsis RPS6 genes, encoding for cytoplasmic ribosomal proteins S6, are functionally equivalent. Creff A, et al. Plant Mol Biol, 2010 Jul. PMID 20437080
    2. Ribosomal protein S6, a target of rapamycin, is involved in the regulation of rRNA genes by possible epigenetic changes in Arabidopsis. Kim YK, et al. J Biol Chem, 2014 Feb 14. PMID 24302738, Free PMC Article
    3. Identification of nucleosome assembly protein 1 (NAP1) as an interacting partner of plant ribosomal protein S6 (RPS6) and a positive regulator of rDNA transcription. Son O, et al. Biochem Biophys Res Commun, 2015 Sep 18. PMID 26241676
    4. Pathogen effectors target Arabidopsis EDS1 and alter its interactions with immune regulators. Bhattacharjee S, et al. Science, 2011 Dec 9. PMID 22158819
    5. Interactome of the plant-specific ESCRT-III component AtVPS2.2 in Arabidopsis thaliana. Ibl V, et al. J Proteome Res, 2012 Jan 1. PMID 22010978, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. NAP1 plays a positive regulatory role in plant rDNA transcription, possibly through derepression of the negative effect of the RPS6-HD2B complex.
      Title: Identification of nucleosome assembly protein 1 (NAP1) as an interacting partner of plant ribosomal protein S6 (RPS6) and a positive regulator of rDNA transcription.
    2. the interaction between RPS6 and AtHD2B brings about a change in the chromatin structure of rDNA and thus plays an important role in linking TOR signaling to rDNA transcription and ribosome biogenesis in plants.
      Title: Ribosomal protein S6, a target of rapamycin, is involved in the regulation of rRNA genes by possible epigenetic changes in Arabidopsis.
    3. RPS6 function is indispensable for cell survival and the two Arabidopsis RPS6 proteins are functionally indistinguishable. [RPS6A]
      Title: The two Arabidopsis RPS6 genes, encoding for cytoplasmic ribosomal proteins S6, are functionally equivalent.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001085006.1
    NM_119319.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    NOT located_in Golgi apparatus RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in cytosolic ribosome HDA PubMed 
    part_of cytosolic small ribosomal subunit HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleolus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    ribosomal protein S6
    NP_001078475.1
    • ribosomal protein S6 (RPS6); FUNCTIONS IN: structural constituent of ribosome; INVOLVED IN: growth, translation; LOCATED IN: cytosolic small ribosomal subunit, plasma membrane, membrane; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ribosomal protein S6e (InterPro:IPR001377); BEST Arabidopsis thaliana protein match is: Ribosomal protein S6e (TAIR:AT5G10360.1); Has 870 Blast hits to 868 proteins in 314 species: Archae - 19; Bacteria - 0; Metazoa - 402; Fungi - 166; Plants - 138; Viruses - 0; Other Eukaryotes - 145 (source: NCBI BLink).
    NP_194898.1
    • ribosomal protein S6 (RPS6); FUNCTIONS IN: structural constituent of ribosome; INVOLVED IN: growth, translation; LOCATED IN: in 6 components; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ribosomal protein S6e (InterPro:IPR001377), Ribosomal protein S6, eukaryotic (InterPro:IPR014401); BEST Arabidopsis thaliana protein match is: Ribosomal protein S6e (TAIR:AT5G10360.1); Has 1159 Blast hits to 1155 proteins in 426 species: Archae - 247; Bacteria - 0; Metazoa - 418; Fungi - 171; Plants - 143; Viruses - 0; Other Eukaryotes - 180 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      15345979..15347804 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119319.5 → NP_194898.1  ribosomal protein S6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194898.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O48549, O81777
      UniProtKB/TrEMBL
      A0A5S9XYJ5, A0A654FUP3, A0A7G2F3V6
      Conserved Domains (1) summary
      cl00931
      Location:1 → 225
      Ribosomal_S6e; Ribosomal protein S6e

    2. NM_001085006.1 → NP_001078475.1  ribosomal protein S6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078475.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8MS03
      Conserved Domains (1) summary
      cl00931
      Location:1 → 163
      Ribosomal_S6e; Ribosomal protein S6e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O48549.2

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