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    DEL2 DP-E2F-like 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831348, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DEL2
    Official Full Name
    DP-E2F-like 2
    Primary source
    TAIR:AT5G14960
    Locus tag
    AT5G14960
    See related
    Araport:AT5G14960
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DP-E2F-like 2; E2FD; E2L1; F2G14.80; F2G14_80
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    Genomic context

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    See DEL2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Sequence:
    Chromosome: 5; NC_003076.8 (4843855..4846664)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily protein Neighboring gene golgi alpha-mannosidase II Neighboring gene seed maturation-like protein Neighboring gene alpha/beta-Hydrolases superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The E2FD/DEL2 factor is a component of a regulatory network controlling cell proliferation and development in Arabidopsis. Sozzani R, et al. Plant Mol Biol, 2010 Mar. PMID 19937368
    2. The E2F family of transcription factors from Arabidopsis thaliana. Novel and conserved components of the retinoblastoma/E2F pathway in plants. Mariconti L, et al. J Biol Chem, 2002 Mar 22. PMID 11786543
    3. E2Ls, E2F-like repressors of Arabidopsis that bind to E2F sites in a monomeric form. Kosugi S, et al. J Biol Chem, 2002 May 10. PMID 11867638
    4. Functional modules in the Arabidopsis core cell cycle binary protein-protein interaction network. Boruc J, et al. Plant Cell, 2010 Apr. PMID 20407024, Free PMC Article
    5. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Efroni I, et al. Dev Cell, 2013 Feb 25. PMID 23449474, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. E2FD/DEL2 accumulation is subject to negative post-translational regulation mediated by the plant hormone auxin.
      Title: The E2FD/DEL2 factor is a component of a regulatory network controlling cell proliferation and development in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to auxin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DP-E2F-like 2
    NP_197000.1
    • DP-E2F-like 2 (DEL2); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: nucleus; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Transcription factor E2F/dimerisation partner (TDP) (InterPro:IPR003316), E2F Family (InterPro:IPR015633); BEST Arabidopsis thaliana protein match is: DP-E2F-like protein 3 (TAIR:AT3G01330.1); Has 936 Blast hits to 860 proteins in 115 species: Archae - 0; Bacteria - 0; Metazoa - 583; Fungi - 5; Plants - 220; Viruses - 0; Other Eukaryotes - 128 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      4843855..4846664
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121500.4 → NP_197000.1  DP-E2F-like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197000.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LFQ9
      UniProtKB/TrEMBL
      A0A178UM45, A0A5S9Y4I7
      Conserved Domains (1) summary
      pfam02319
      Location:15 → 78
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain

    2. NM_001343379.1 → NP_001330250.1  DP-E2F-like 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BA83
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LFQ9.1

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