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    BCB blue-copper-binding protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832145, updated on 18-Sep-2024

    Summary

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    Official Symbol
    BCB
    Official Full Name
    blue-copper-binding protein
    Primary source
    TAIR:AT5G20230
    Locus tag
    AT5G20230
    See related
    Araport:AT5G20230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATBCB; BLUE COPPER BINDING PROTEIN; blue-copper-binding protein; F5O24.120; F5O24_120; SAG14; SENESCENCE ASSOCIATED GENE 14
    Summary
    Al-stress-induced gene
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    Genomic context

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    See BCB in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (6826365..6827748)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene nucleoporin-like protein Neighboring gene zinc knuckle (CCHC-type) family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene K-box region and MADS-box transcription factor family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Different mechanisms of four aluminum (Al)-resistant transgenes for Al toxicity in Arabidopsis. Ezaki B, et al. Plant Physiol, 2001 Nov. PMID 11706174, Free PMC Article
    2. Expression of aluminum-induced genes in transgenic arabidopsis plants can ameliorate aluminum stress and/or oxidative stress. Ezaki B, et al. Plant Physiol, 2000 Mar. PMID 10712528, Free PMC Article
    3. A negatively light-regulated gene from Arabidopsis thaliana encodes a protein showing high similarity to blue copper-binding proteins. Van Gysel A, et al. Gene, 1993 Dec 22. PMID 8294044
    4. The Arabidopsis RCC1 Family Protein TCF1 Regulates Freezing Tolerance and Cold Acclimation through Modulating Lignin Biosynthesis. Ji H, et al. PLoS Genet, 2015. PMID 26393916, Free PMC Article
    5. Bacterial non-host resistance: interactions of Arabidopsis with non-adapted Pseudomonas syringae strains. Mishina TE, et al. Physiol Plant, 2007 Nov. PMID 18251883

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The pal1pal2 double mutant (lignin content reduced by 30% compared with WT) also showed the freezing tolerant phenotype, and TCF1 and BCB act upstream of PALs to regulate lignin content.
      Title: The Arabidopsis RCC1 Family Protein TCF1 Regulates Freezing Tolerance and Cold Acclimation through Modulating Lignin Biosynthesis.
    2. Data show type III secretion system-independent upregulation of BCB, which might contribute to an early induced, cell wall-based defence mechanism, occurs in response to non-adapted bacteria.
      Title: Bacterial non-host resistance: interactions of Arabidopsis with non-adapted Pseudomonas syringae strains.
    3. The effects of AtBCB and NtGDI1 on aluminum tolerance in plants and S. cerevisiae are reported.
      Title: Functions of two genes in aluminium (Al) stress resistance: repression of oxidative damage by the AtBCB gene and promotion of efflux of Al ions by the NtGDI1gene.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_122030.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables electron transfer activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within aluminum cation transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to cold IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    acts_upstream_of_or_within regulation of lignin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to absence of light IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to oomycetes IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to oxidative stress TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to wounding IEP
    Inferred from Expression Pattern
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    blue-copper-binding protein
    NP_197523.1
    • blue-copper-binding protein (BCB); FUNCTIONS IN: electron carrier activity, copper ion binding; INVOLVED IN: response to oxidative stress, response to salt stress, aluminum ion transport, response to wounding, response to absence of light; LOCATED IN: anchored to plasma membrane, plasma membrane, vacuole, anchored to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Plastocyanin-like (InterPro:IPR003245), Cupredoxin (InterPro:IPR008972), Blue (type 1) copper domain (InterPro:IPR000923); BEST Arabidopsis thaliana protein match is: Cupredoxin superfamily protein (TAIR:AT1G72230.1); Has 2817 Blast hits to 1998 proteins in 202 species: Archae - 2; Bacteria - 847; Metazoa - 51; Fungi - 106; Plants - 1463; Viruses - 11; Other Eukaryotes - 337 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      6826365..6827748
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122030.4 → NP_197523.1  blue-copper-binding protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197523.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82664, Q07488
      UniProtKB/TrEMBL
      A0A178UM84, A0A5S9Y5S9
      Conserved Domains (1) summary
      cd13920
      Location:23 → 123
      Stellacyanin; Stellacyanin is a subclass of phytocyanins, a plant type I copper protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q07488.2

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