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    MTO3 S-adenosylmethionine synthetase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821003, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MTO3
    Official Full Name
    S-adenosylmethionine synthetase family protein
    Primary source
    TAIR:AT3G17390
    Locus tag
    AT3G17390
    See related
    Araport:AT3G17390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MAT4; METHIONINE ADENOSYLTRANSFERASE 4; METHIONINE OVER-ACCUMULATOR 3; S-ADENOSYLMETHIONINE SYNTHETASE; S-ADENOSYLMETHIONINE SYNTHETASE 3; SAMS3
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    Genomic context

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    See MTO3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (5952187..5954091, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene TRAF-like family protein Neighboring gene ncRNA Neighboring gene F-box family protein Neighboring gene Protein kinase superfamily protein Neighboring gene glyoxysomal protein kinase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. METHIONINE ADENOSYLTRANSFERASE4 Mediates DNA and Histone Methylation. Meng J, et al. Plant Physiol, 2018 Jun. PMID 29572390, Free PMC Article
    2. High free-methionine and decreased lignin content result from a mutation in the Arabidopsis S-adenosyl-L-methionine synthetase 3 gene. Shen B, et al. Plant J, 2002 Feb. PMID 11844113
    3. Proteome analysis of cold stress response in Arabidopsis thaliana using DIGE-technology. Amme S, et al. J Exp Bot, 2006. PMID 16574749
    4. Identification of enzymes for adenosine-to-inosine editing and discovery of cytidine-to-uridine editing in nucleus-encoded transfer RNAs of Arabidopsis. Zhou W, et al. Plant Physiol, 2014 Dec. PMID 25315605, Free PMC Article
    5. Organizer-Derived WOX5 Signal Maintains Root Columella Stem Cells through Chromatin-Mediated Repression of CDF4 Expression. Pi L, et al. Dev Cell, 2015 Jun 8. PMID 26028217

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MAT4 plays a predominant role in S-adenosylmethionine production, plant growth, and development.
      Title: METHIONINE ADENOSYLTRANSFERASE4 Mediates DNA and Histone Methylation.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_112618.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables methionine adenosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in S-adenosylmethionine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within lignin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within methionine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in nucleolus HDA PubMed 
    located_in plant-type cell wall HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    S-adenosylmethionine synthetase family protein
    NP_188365.1
    • METHIONINE OVER-ACCUMULATOR 3 (MTO3); FUNCTIONS IN: methionine adenosyltransferase activity; INVOLVED IN: lignin biosynthetic process, response to cold, methionine metabolic process, S-adenosylmethionine biosynthetic process; LOCATED IN: nucleolus, cell wall, plasma membrane, membrane; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: S-adenosylmethionine synthetase (InterPro:IPR002133), S-adenosylmethionine synthetase superfamily (InterPro:IPR022636), S-adenosylmethionine synthetase, N-terminal (InterPro:IPR022628), S-adenosylmethionine synthetase, C-terminal (InterPro:IPR022630), S-adenosylmethionine synthetase, conserved site (InterPro:IPR022631), S-adenosylmethionine synthetase, central domain (InterPro:IPR022629); BEST Arabidopsis thaliana protein match is: S-adenosylmethionine synthetase 1 (TAIR:AT1G02500.2); Has 10856 Blast hits to 10849 proteins in 2868 species: Archae - 12; Bacteria - 5440; Metazoa - 373; Fungi - 167; Plants - 707; Viruses - 1; Other Eukaryotes - 4156 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5952187..5954091 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112618.4 → NP_188365.1  S-adenosylmethionine synthetase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188365.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WLR3, Q9LUT2
      UniProtKB/TrEMBL
      A0A178VIP8, A0A5S9XCZ4, A0A654E6D0
      Conserved Domains (1) summary
      PLN02243
      Location:1 → 386
      PLN02243; S-adenosylmethionine synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LUT2.1

    Gene LinkOut

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