ECT2 evolutionarily conserved C-terminal region 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ECT2
Official Full Name: evolutionarily conserved C-terminal region 2
Primary source: TAIR:AT3G13460
Locus tag: AT3G13460
See related: Araport:AT3G13460
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: evolutionarily conserved C-terminal region 2
Summary: Physically interacts with CIPK1.
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Genomic context

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See ECT2 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 9

Sequence:: Chromosome: 3; NC_003074.8 (4384563..4388592, complement)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ECT2 peptide sequences outside the YTH domain regulate its m[6]A-RNA binding.
Title: ECT2 peptide sequences outside the YTH domain regulate its m(6)A-RNA binding.
m[6]A readers ECT2/ECT3/ECT4 enhance mRNA stability through direct recruitment of the poly(A) binding proteins in Arabidopsis.
Title: m(6)A readers ECT2/ECT3/ECT4 enhance mRNA stability through direct recruitment of the poly(A) binding proteins in Arabidopsis.
Principles of mRNA targeting via the Arabidopsis m(6)A-binding protein ECT2.
Title: Principles of mRNA targeting via the Arabidopsis m(6)A-binding protein ECT2.
The YTHDF proteins ECT2 and ECT3 bind largely overlapping target sets and influence target mRNA abundance, not alternative polyadenylation.
Title: The YTHDF proteins ECT2 and ECT3 bind largely overlapping target sets and influence target mRNA abundance, not alternative polyadenylation.
The m(6) A reader ECT2 post-transcriptionally regulates proteasome activity in Arabidopsis.
Title: The m(6) A reader ECT2 post-transcriptionally regulates proteasome activity in Arabidopsis.
Recurrent requirement for the m(6)A-ECT2/ECT3/ECT4 axis in the control of cell proliferation during plant organogenesis.
Title: Recurrent requirement for the m(6)A-ECT2/ECT3/ECT4 axis in the control of cell proliferation during plant organogenesis.
ECT proteins, ECT1 and ECT2, are molecular components in the CBL-CIPK calcium signaling pathways. They contain a highly conserved 180-amino acid region, which is involved in mediating the nuclear localization of the ECT proteins. [ECT2]
Title: Novel CIPK1-associated proteins in Arabidopsis contain an evolutionarily conserved C-terminal region that mediates nuclear localization.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001035612.1

Supported by ESTs:

NM_001035613.1

Supported by ESTs:

NM_112192.5

Supported by ESTs:

NM_180247.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables mRNA binding	HDA more info	PubMed
enables mRNA binding	IDA Inferred from Direct Assay more info	PubMed
enables mRNA binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in mRNA stabilization	IGI Inferred from Genetic Interaction more info	PubMed
involved_in response to abscisic acid	IGI Inferred from Genetic Interaction more info	PubMed
involved_in response to virus	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasmic stress granule	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	HDA more info	PubMed
located_in nucleus	HDA more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: evolutionarily conserved C-terminal region 2

NP_001030689.1

evolutionarily conserved C-terminal region 2 (ECT2); FUNCTIONS IN: protein binding; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: YTH domain (InterPro:IPR007275); BEST Arabidopsis thaliana protein match is: evolutionarily conserved C-terminal region 4 (TAIR:AT1G55500.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NP_001030690.1

evolutionarily conserved C-terminal region 2 (ECT2); FUNCTIONS IN: protein binding; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: YTH domain (InterPro:IPR007275); BEST Arabidopsis thaliana protein match is: evolutionarily conserved C-terminal region 4 (TAIR:AT1G55500.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NP_187955.2

evolutionarily conserved C-terminal region 2 (ECT2); FUNCTIONS IN: protein binding; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: YTH domain (InterPro:IPR007275); BEST Arabidopsis thaliana protein match is: evolutionarily conserved C-terminal region 4 (TAIR:AT1G55500.2); Has 1777 Blast hits to 1661 proteins in 257 species: Archae - 0; Bacteria - 83; Metazoa - 881; Fungi - 229; Plants - 416; Viruses - 0; Other Eukaryotes - 168 (source: NCBI BLink).

NP_850578.1

evolutionarily conserved C-terminal region 2 (ECT2); FUNCTIONS IN: protein binding; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: YTH domain (InterPro:IPR007275); BEST Arabidopsis thaliana protein match is: evolutionarily conserved C-terminal region 4 (TAIR:AT1G55500.2); Has 1772 Blast hits to 1656 proteins in 254 species: Archae - 0; Bacteria - 82; Metazoa - 884; Fungi - 229; Plants - 410; Viruses - 0; Other Eukaryotes - 167 (source: NCBI BLink).