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    EMB2271 Transducin/WD40 repeat-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827861, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EMB2271
    Official Full Name
    Transducin/WD40 repeat-like superfamily protein
    Primary source
    TAIR:AT4G21130
    Locus tag
    AT4G21130
    See related
    Araport:AT4G21130
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EMBRYO DEFECTIVE 2271; F7J7.70; F7J7_70
    Summary
    similar to man and yeast U3-55K genes, involved in processing of pre-ribosomal RNA.
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    Genomic context

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    See EMB2271 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (11274296..11276299)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene G10 family protein Neighboring gene amino acid transporter 1 Neighboring gene copper ion-binding protein Neighboring gene ribophorin II (RPN2) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An approach towards experimental cDNA sequence determination of predicted genes: an example from Arabidopsis U3-55k homologues. Urbánek P, et al. Gene, 2005 Sep 26. PMID 16054306
    2. Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases. Lee JH, et al. Plant Cell, 2008 Jan. PMID 18223036, Free PMC Article
    3. Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes. Zhang Y, et al. Plant Cell, 2008 Jun. PMID 18552200, Free PMC Article
    4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_118232.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables U3 snoRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    acts_upstream_of_or_within rRNA processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Transducin/WD40 repeat-like superfamily protein
    NP_193845.2
    • EMBRYO DEFECTIVE 2271 (EMB2271); CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40 repeat, conserved site (InterPro:IPR019775), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat (InterPro:IPR001680), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT4G05410.1); Has 39777 Blast hits to 20460 proteins in 714 species: Archae - 46; Bacteria - 6502; Metazoa - 14728; Fungi - 8617; Plants - 4380; Viruses - 43; Other Eukaryotes - 5461 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      11274296..11276299
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118232.2 → NP_193845.2  Transducin/WD40 repeat-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193845.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49554, Q3MKM6
      UniProtKB/TrEMBL
      A0A178UZM4, A0A5S9XUG5
      Conserved Domains (3) summary
      COG2319
      Location:143 → 448
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:148 → 204
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:125 → 415
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3MKM6.1

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