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    KCS19 3-ketoacyl-CoA synthase 19 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830332, updated on 18-Sep-2024

    Summary

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    Official Symbol
    KCS19
    Official Full Name
    3-ketoacyl-CoA synthase 19
    Primary source
    TAIR:AT5G04530
    Locus tag
    AT5G04530
    See related
    Araport:AT5G04530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    3-ketoacyl-CoA synthase 19; T32M21.130; T32M21_130
    Summary
    Encodes KCS19, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
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    Genomic context

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    See KCS19 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (1291630..1293723, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene glycosyltransferase family protein 47 Neighboring gene 3'-phosphoinositide-dependent protein kinase 1 Neighboring gene 3-oxoacyl-acyl-carrier synthase-like protein (Protein of unknown function DUF455) Neighboring gene ncRNA Neighboring gene Myotubularin-like phosphatases II superfamily

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the closely related Arabidopsis thaliana β-ketoacyl-CoA synthases KCS3, KCS12 and KCS19. Zhang Z, et al. Plant J, 2024 Jul. PMID 38666591
    2. The VLCFA elongase gene family in Arabidopsis thaliana: phylogenetic analysis, 3D modelling and expression profiling. Joubès J, et al. Plant Mol Biol, 2008 Jul. PMID 18465198
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Characterization of the closely related Arabidopsis thaliana beta-ketoacyl-CoA synthases KCS3, KCS12 and KCS19.
      Title: Characterization of the closely related Arabidopsis thaliana β-ketoacyl-CoA synthases KCS3, KCS12 and KCS19.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_120535.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables fatty acid elongase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to light stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    3-ketoacyl-CoA synthase 19
    NP_196073.1
    • 3-ketoacyl-CoA synthase 19 (KCS19); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, catalytic activity, acyltransferase activity; INVOLVED IN: response to cold, response to light stimulus, response to osmotic stress; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), Very-long-chain 3-ketoacyl-CoA synthase (InterPro:IPR012392), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), FAE1/Type III polyketide synthase-like protein (InterPro:IPR013601), Thiolase-like, subgroup (InterPro:IPR016038); BEST Arabidopsis thaliana protein match is: 3-ketoacyl-CoA synthase 12 (TAIR:AT2G28630.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1291630..1293723 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120535.3 → NP_196073.1  3-ketoacyl-CoA synthase 19 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196073.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LZ72
      UniProtKB/TrEMBL
      A0A178UE05, A0A5S9Y1M4
      Conserved Domains (2) summary
      pfam08392
      Location:24 → 317
      FAE1_CUT1_RppA; FAE1/Type III polyketide synthase-like protein
      cl21486
      Location:337 → 410
      Ketoacyl-synt_C; Beta-ketoacyl synthase, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LZ72.1

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