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    AIL5 AINTEGUMENTA-like 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835845, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AIL5
    Official Full Name
    AINTEGUMENTA-like 5
    Primary source
    TAIR:AT5G57390
    Locus tag
    AT5G57390
    See related
    Araport:AT5G57390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AINTEGUMENTA-like 5; CHO1; CHOTTO 1; EMBRYOMAKER; EMK; MSF19.5; MSF19_5; PLETHORA 5; PLT5
    Summary
    Encodes a member of the AP2 family of transcriptional regulators. May be involved in germination and seedling growth. Mutants are resistant to ABA analogs and are resistant to high nitrogen concentrations.essential for the developmental transition between the embryonic and vegetative phases in plants. Overexpression results in the formation of somatic embryos on cotyledons. It is also required to maintain high levels of PIN1 expression at the periphery of the meristem and modulate local auxin production in the central region of the SAM which underlies phyllotactic transitions.
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    Genomic context

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    See AIL5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Sequence:
    Chromosome: 5; NC_003076.8 (23252989..23256703, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene U4/U6.U5 small nuclear ribonucleoprotein Neighboring gene Fibronectin type III domain-containing protein Neighboring gene uncharacterized protein Neighboring gene Afadin/alpha-actinin-binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CHOTTO1, a double AP2 domain protein of Arabidopsis thaliana, regulates germination and seedling growth under excess supply of glucose and nitrate. Yamagishi K, et al. Plant Cell Physiol, 2009 Feb. PMID 19109301
    2. Arabidopsis EMBRYOMAKER encoding an AP2 domain transcription factor plays a key role in developmental change from vegetative to embryonic phase. Tsuwamoto R, et al. Plant Mol Biol, 2010 Jul. PMID 20405311
    3. CHOTTO1, a putative double APETALA2 repeat transcription factor, is involved in abscisic acid-mediated repression of gibberellin biosynthesis during seed germination in Arabidopsis. Yano R, et al. Plant Physiol, 2009 Oct. PMID 19648230, Free PMC Article
    4. Gene networks and chromatin and transcriptional regulation of the phaseolin promoter in Arabidopsis. Sundaram S, et al. Plant Cell, 2013 Jul. PMID 23872538, Free PMC Article
    5. Differences in both expression and protein activity contribute to the distinct functions of AINTEGUMENTA compared with AINTEGUMENTA-LIKE 5 and AINTEGUMENTA-LIKE 7. Krizek BA, et al. Plant Mol Biol, 2023 Oct. PMID 37606746, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Differences in both expression and protein activity contribute to the distinct functions of AINTEGUMENTA compared with AINTEGUMENTA-LIKE 5 and AINTEGUMENTA-LIKE 7.
      Title: Differences in both expression and protein activity contribute to the distinct functions of AINTEGUMENTA compared with AINTEGUMENTA-LIKE 5 and AINTEGUMENTA-LIKE 7.
    2. This study characterized the effects of three PLETHORA (PLT) transcription factors, PLT3, PLT5, and PLT7, during lateral root outgrowth.
      Title: PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth.
    3. AIL genes exhibit unequal genetic redundancy with roles for AIL5, AIL6, and AIL7 only revealed in the absence of ANT function. AIL5, AIL6, and AIL7 act in a dose dependent manners in ant and other mutant backgrounds.
      Title: AINTEGUMENTA-LIKE genes have partly overlapping functions with AINTEGUMENTA but make distinct contributions to Arabidopsis thaliana flower development.
    4. In A. thaliana, three transcriptional regulators implicated in phyllotaxis, PLETHORA3 (PLT3), PLT5, and PLT7, are expressed in incipient lateral root primordia where they are required for primordium development and lateral root emergence.[PLT5]
      Title: Phyllotaxis and rhizotaxis in Arabidopsis are modified by three PLETHORA transcription factors.
    5. PLT proteins are key regulators of PIN1 activity in control of phyllotaxis. PLT3, PLT5, and PLT7 are essential for normal phyllotaxis. [PLT5]
      Title: Arabidopsis PLETHORA transcription factors control phyllotaxis.
    6. Data indicate that transcriptional regulators RINGLET 2 (RLT2; AT5G44180) and AINTEGUMENTA-LIKE 5 (AIL5; At5g57390) as being essential for transgene phas transcription.
      Title: Gene networks and chromatin and transcriptional regulation of the phaseolin promoter in Arabidopsis.
    7. AtEMK is a key player to maintain embryonic identity, and the rapid disappearance of AtEMK expression during germination is essential for the developmental transition between the embryonic and vegetative phases in plants. [AtEMK]
      Title: Arabidopsis EMBRYOMAKER encoding an AP2 domain transcription factor plays a key role in developmental change from vegetative to embryonic phase.
    8. CHO1 acts downstream of abscisic acid to repress gibberellins biosynthesis during seed germination.
      Title: CHOTTO1, a putative double APETALA2 repeat transcription factor, is involved in abscisic acid-mediated repression of gibberellin biosynthesis during seed germination in Arabidopsis.
    9. CHOTTO1 (CHO1) encodes a double AP2 transcription factor and acts downstream of ABI4. CHO1 regulates nutritional responses downstream of ABI4 during germination and seedling growth. [CHO1]
      Title: CHOTTO1, a double AP2 domain protein of Arabidopsis thaliana, regulates germination and seedling growth under excess supply of glucose and nitrate.
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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001345261.1
    NM_125122.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within callus formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within lateral root formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf phyllotactic patterning IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within phyllotactic patterning IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within plant organ morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within post-embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within seed germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    AINTEGUMENTA-like 5
    NP_200549.2
    • AINTEGUMENTA-like 5 (AIL5); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: Integrase-type DNA-binding superfamily protein (TAIR:AT3G20840.1); Has 9099 Blast hits to 5771 proteins in 325 species: Archae - 0; Bacteria - 38; Metazoa - 238; Fungi - 101; Plants - 7378; Viruses - 6; Other Eukaryotes - 1338 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      23252989..23256703 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125122.4 → NP_200549.2  AINTEGUMENTA-like 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200549.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6PQQ3, Q9FIE2
      UniProtKB/TrEMBL
      A0A5S9YF03, A0A654GCA0
      Conserved Domains (1) summary
      smart00380
      Location:306 → 369
      AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs

    2. NM_001345261.1 → NP_001331405.1  AINTEGUMENTA-like 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178U889, A0A1P8BDT2, A0A384LBF4, A0A7G2FJX6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6PQQ3.2

    Gene LinkOut

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