PAKRP1 phragmoplast-associated kinesin-related protein 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: PAKRP1
Official Full Name: phragmoplast-associated kinesin-related protein 1
Primary source: TAIR:AT4G14150
Locus tag: AT4G14150
See related: Araport:AT4G14150
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: DL3115C; FCAALL.159; KINESIN-12A; phragmoplast-associated kinesin-related protein 1
Summary: Microtubule motor kinesin PAKRP1/Kinesin-12A. Together with PAKRP1L/Kinesin-12B, serve as linkers of the plus ends of antiparallel microtubules in the phragmoplast.
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

TIO and Kinesin-12 constitute a signalling module that is required to support phragmoplast expansion and cell-plate growth in plant cells.
Title: Arabidopsis Fused kinase and the Kinesin-12 subfamily constitute a signalling module required for phragmoplast expansion.
Kinesin-12 members serve as dynamic linkers of the plus ends of antiparallel microtubules in the phragmoplast.
Title: Two Arabidopsis phragmoplast-associated kinesins play a critical role in cytokinesis during male gametogenesis.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_117492.2

Function	Evidence Code	Pubs
enables microtubule binding	IEA Inferred from Electronic Annotation more info
enables microtubule motor activity	IEA Inferred from Electronic Annotation more info
enables plus-end-directed microtubule motor activity	IGI Inferred from Genetic Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within male meiosis cytokinesis	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within microgametogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in microtubule-based movement	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phragmoplast assembly	IGI Inferred from Genetic Interaction more info	PubMed
involved_in phragmoplast microtubule organization	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in phragmoplast	IDA Inferred from Direct Assay more info	PubMed

NP_567423.1

phragmoplast-associated kinesin-related protein 1 (PAKRP1); CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Kinesin-related protein (InterPro:IPR010544), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: phragmoplast-associated kinesin-related protein, putative (TAIR:AT3G23670.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

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